CHMP6 gene

The endosomal sorting complex required for transport (ESCRT) facilitates roles in membrane remodeling, such as multivesicular… (More)

Recently the ESCRT-III filamentous complex was designated as the driving force for mammalian cell abscission, that is, fission of… (More)

While Ras GTPases are best known for mediating growth factor signaling on the plasma membrane, these proteins also have… (More)

The endosomal sorting complex required for transport (ESCRT) system traffics ubiquitinated cargo to lysosomes via an unusual… (More)

While Ras is well-known to function on the plasma membrane (PM) to mediate growth factor signaling, increasing evidence suggests… (More)

Budding of retroviruses from cell membranes requires ubiquitination of Gag and recruitment of cellular proteins involved in… (More)

Cell death can proceed via at least two distinct pathways, apoptosis and oncosis. Apoptosis is an energy-dependent process… (More)

Sorting of ubiquitylated cargo proteins, such as transmembrane receptors, into multivesicular bodies (endosomes filled with… (More)

CHMP6 (charged multivesicular body protein 6) is a human orthologue of yeast Vps (vacuolar protein sorting) 20, a component of… (More)

Vps4p (End13p) is an AAA-family ATPase that functions in membrane transport through endosomes, sorting of soluble vacuolar… (More)