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CHMP6 gene

Known as: FLJ11749, CHMP FAMILY, MEMBER 6, CHMP6 
 
National Institutes of Health

Related topics

Related topics

1 relation
CHMP4B gene

Papers overview

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Highly Cited
2012
Highly Cited
2012
Amyloid precursor protein (APP) traffics from the cell surface via endosomes for amyloid β (Aβ) production in the trans-Golgi network
Amyloid precursor protein (APP) is processed sequentially by the β-site APP cleaving enzyme and γ-secretase to generate amyloid… Expand
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Highly Cited
2010
Highly Cited
2010
ESCRT‐II coordinates the assembly of ESCRT‐III filaments for cargo sorting and multivesicular body vesicle formation
The sequential action of five distinct endosomal‐sorting complex required for transport (ESCRT) complexes is required for the… Expand
Highly Cited
2010
Highly Cited
2010
Activation of Human VPS4A by ESCRT-III Proteins Reveals Ability of Substrates to Relieve Enzyme Autoinhibition*
VPS4 proteins are AAA+ ATPases required to form multivesicular bodies, release viral particles, and complete cytokinesis. They… Expand
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Highly Cited
2009
Highly Cited
2009
Membrane scission by the ESCRT-III complex
The endosomal sorting complex required for transport (ESCRT) system is essential for multivesicular body biogenesis, in which… Expand
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Highly Cited
2009
Highly Cited
2009
Structure and function of the ESCRT-II-III interface in multivesicular body biogenesis.
The ESCRT-II-ESCRT-III interaction coordinates the sorting of ubiquitinated cargo with the budding and scission of intralumenal… Expand
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Highly Cited
2009
Highly Cited
2009
Computational Model of Membrane Fission Catalyzed by ESCRT-III
ESCRT-III proteins catalyze membrane fission during multi vesicular body biogenesis, budding of some enveloped viruses and cell… Expand
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Highly Cited
2008
Highly Cited
2008
Ordered assembly of the ESCRT-III complex on endosomes is required to sequester cargo during MVB formation.
The sequential action of the Vps27/HRS complex, ESCRT-I, -II, and -III is required to sort ubiquitinated transmembrane proteins… Expand
Highly Cited
2008
Highly Cited
2008
Two distinct modes of ESCRT-III recognition are required for VPS4 functions in lysosomal protein targeting and HIV-1 budding.
The ESCRT pathway mediates membrane remodeling during enveloped virus budding, cytokinesis, and intralumenal endosomal vesicle… Expand
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Highly Cited
2005
Highly Cited
2005
Human CHMP6, a myristoylated ESCRT-III protein, interacts directly with an ESCRT-II component EAP20 and regulates endosomal cargo sorting.
CHMP6 (charged multivesicular body protein 6) is a human orthologue of yeast Vps (vacuolar protein sorting) 20, a component of… Expand
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Highly Cited
2002
Highly Cited
2002
Escrt-III: an endosome-associated heterooligomeric protein complex required for mvb sorting.
The sorting of transmembrane proteins (e.g., cell surface receptors) into the multivesicular body (MVB) pathway to the lysosomal… Expand
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