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CHMP6 gene

Known as: FLJ11749, CHMP FAMILY, MEMBER 6, CHMP6 
 
National Institutes of Health

Related topics

Related topics

1 relation
CHMP4B gene

Papers overview

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Highly Cited
2015
Highly Cited
2015
Negative membrane curvature catalyzes nucleation of endosomal sorting complex required for transport (ESCRT)-III assembly
Significance The endosomal sorting complex required for transport (ESCRT) proteins remodel and sever membranes in a wide range of… Expand
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2014
2014
Inhibition of ESCRT-II–CHMP6 interactions impedes cytokinetic abscission and leads to cell death
Mammalian cell abscission was recently shown to be driven by the ESCRT machinery, but the mechanism has not been fully resolved… Expand
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Highly Cited
2012
Highly Cited
2012
In vitro reconstitution of the ordered assembly of the endosomal sorting complex required for transport at membrane-bound HIV-1 Gag clusters
Most membrane-enveloped viruses depend on host proteins of the endosomal sorting complex required for transport (ESCRT) machinery… Expand
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2011
2011
Rescue of Aspergillus nidulans severely debilitating null mutations in ESCRT-0, I, II and III genes by inactivation of a salt-tolerance pathway allows examination of ESCRT gene roles in pH signalling
The Aspergillus pal pathway hijacks ESCRT proteins into ambient pH signalling complexes. We show that components of ESCRT-0… Expand
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Highly Cited
2009
Highly Cited
2009
Membrane scission by the ESCRT-III complex
The endosomal sorting complex required for transport (ESCRT) system is essential for multivesicular body biogenesis, in which… Expand
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Highly Cited
2009
Highly Cited
2009
Computational Model of Membrane Fission Catalyzed by ESCRT-III
ESCRT-III proteins catalyze membrane fission during multi vesicular body biogenesis, budding of some enveloped viruses and cell… Expand
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Highly Cited
2008
Highly Cited
2008
Ordered assembly of the ESCRT-III complex on endosomes is required to sequester cargo during MVB formation.
The sequential action of the Vps27/HRS complex, ESCRT-I, -II, and -III is required to sort ubiquitinated transmembrane proteins… Expand
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Highly Cited
2005
Highly Cited
2005
Human CHMP6, a myristoylated ESCRT-III protein, interacts directly with an ESCRT-II component EAP20 and regulates endosomal cargo sorting.
CHMP6 (charged multivesicular body protein 6) is a human orthologue of yeast Vps (vacuolar protein sorting) 20, a component of… Expand
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Highly Cited
2003
Highly Cited
2003
Vps20p and Vta1p interact with Vps4p and function in multivesicular body sorting and endosomal transport in Saccharomyces cerevisiae
Vps4p (End13p) is an AAA-family ATPase that functions in membrane transport through endosomes, sorting of soluble vacuolar… Expand
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Highly Cited
2002
Highly Cited
2002
Escrt-III: an endosome-associated heterooligomeric protein complex required for mvb sorting.
The sorting of transmembrane proteins (e.g., cell surface receptors) into the multivesicular body (MVB) pathway to the lysosomal… Expand
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