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CHMP2B gene

Known as: VPS2 homolog B (S. cerevisiae), VACUOLAR PROTEIN SORTING 2, YEAST, HOMOLOG OF, B, DKFZP564O123 
 
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
AbstractMutations in the charged multivesicular body protein 2B (CHMP2B) cause frontotemporal dementia (FTD). We report that mice… Expand
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Highly Cited
2014
Highly Cited
2014
Cardiomyocyte proteostasis is mediated by the ubiquitin/proteasome system (UPS) and autophagy/lysosome system and is fundamental… Expand
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2013
2013
Phagophore maturation is a key step in the macroautophagy pathway, which is critical in many important physiological and… Expand
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Highly Cited
2012
Highly Cited
2012
Mutations in the charged multivesicular body protein 2B (CHMP2B) gene cause frontotemporal lobar degeneration. The mutations lead… Expand
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Highly Cited
2011
Highly Cited
2011
Background: ESCRT proteins catalyze membrane budding and fission away from the cytosol. Results: The ESCRT-III protein CHMP2B… Expand
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Highly Cited
2011
Highly Cited
2011
AIMS Granulovacuolar degeneration involves the accumulation of large, double membrane-bound bodies within certain neurones during… Expand
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Highly Cited
2010
Highly Cited
2010
The highly conserved ESCRT-III complex is responsible for deformation and cleavage of membranes during endosomal trafficking and… Expand
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Highly Cited
2009
Highly Cited
2009
Frontotemporal dementia (FTD) is the most common form of dementia before 60 years of age. Rare pathogenic mutations in CHMP2B… Expand
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Highly Cited
2007
Highly Cited
2007
The ESCRT (endosomal sorting complex required for transport) pathway is required for terminal membrane fission events in several… Expand
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Highly Cited
2006
Highly Cited
2006
Mutation in the CHMP2B gene has been implicated in frontotemporal dementia. The authors screened CHMP2B in patients with ALS and… Expand
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