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CHMP2B gene

Known as: VPS2 homolog B (S. cerevisiae), VACUOLAR PROTEIN SORTING 2, YEAST, HOMOLOG OF, B, DKFZP564O123 
National Institutes of Health

Papers overview

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2015
2015
The charged multivesicular body proteins (Chmp1–7) are an evolutionarily conserved family of cytosolic proteins that transiently… Expand
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Highly Cited
2014
Highly Cited
2014
Cardiomyocyte proteostasis is mediated by the ubiquitin/proteasome system (UPS) and autophagy/lysosome system and is fundamental… Expand
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Highly Cited
2012
Highly Cited
2012
Mutations in the charged multivesicular body protein 2B (CHMP2B) gene cause frontotemporal lobar degeneration. The mutations lead… Expand
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Review
2012
Review
2012
Frontotemporal lobar degeneration (FTLD) is a heterogeneous group of disorders characterized by disturbances of behavior and… Expand
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Highly Cited
2011
Highly Cited
2011
Background: ESCRT proteins catalyze membrane budding and fission away from the cytosol. Results: The ESCRT-III protein CHMP2B… Expand
Highly Cited
2011
Highly Cited
2011
K. E. Funk, R. E. Mrak and J. Kuret (2011) Neuropathology and Applied Neurobiology37, 295–306
Granulovacuolar degeneration (GVD… Expand
Highly Cited
2010
Highly Cited
2010
The highly conserved ESCRT-III complex is responsible for deformation and cleavage of membranes during endosomal trafficking and… Expand
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Highly Cited
2009
Highly Cited
2009
Frontotemporal dementia (FTD) is the most common form of dementia before 60 years of age. Rare pathogenic mutations in CHMP2B… Expand
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Highly Cited
2007
Highly Cited
2007
The ESCRT (endosomal sorting complex required for transport) pathway is required for terminal membrane fission events in several… Expand
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Highly Cited
2006
Highly Cited
2006
Mutation in the CHMP2B gene has been implicated in frontotemporal dementia. The authors screened CHMP2B in patients with ALS and… Expand