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CGX-1007
National Institutes of Health
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2011
2011
CGX-1007 prevents excitotoxic cell death via actions at multiple types of NMDA receptors.
A. Alex
,
Gerald W. Saunders
,
Alexandre Dalpé-Charron
,
C. Reilly
,
K. Wilcox
Neurotoxicology
2011
Corpus ID: 35587321
2009
2009
Studies on neuronal apoptoisis in primary forebrain cultures: Neuroprotective/anti-apoptotic action of NR2B NMDA antagonists
J. Dave
,
A. Williams
,
J. Moffett
,
M. Koenig
,
F. Tortella
Neurotoxicity research
2009
Corpus ID: 5200905
While the role of apoptosis in neuronal injury is continually being re-defined, approaches to intervene in the progression of…
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2005
2005
Effects of delayed intrathecal infusion of an NMDA receptor antagonist on ischemic injury and peri-infarct depolarizations
X. Lu
,
A. Williams
,
J. Wagstaff
,
F. Tortella
,
J. Hartings
Brain Research
2005
Corpus ID: 35115948
2004
2004
The effect of CGX-1007 and CI-1041, novel NMDA receptor antagonists, on NMDA receptor-mediated EPSCs
M. Barton
,
H. White
,
K. Wilcox
Epilepsy Research
2004
Corpus ID: 22286038
2004
2004
The effect of CGX-1007 and CI-1041, novel NMDA receptor antagonists, on kindling acquisition and expression
M. Barton
,
H. White
Epilepsy Research
2004
Corpus ID: 23859984
2003
2003
Treatment with the snail peptide CGX-1007 reduces DNA damage and alters gene expression of c-fos and bcl-2 following focal ischemic brain injury in rats
A. Williams
,
G. Ling
,
+5 authors
F. Tortella
Experimental Brain Research
2003
Corpus ID: 2599266
Delayed cell death following ischemic brain injury has been linked to alterations in gene expression. In this study we have…
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Review
2002
Review
2002
Progress report on new antiepileptic drugs: a summary of the Sixth Eilat Conference (EILAT VI)
M. Bialer
,
S. Johannessen
,
H. Kupferberg
,
R. Levy
,
P. Loiseau
,
E. Perucca
Epilepsy Research
2002
Corpus ID: 42996045
Review
2002
Review
2002
Novel anticonvulsant medications in development
C. Hovinga
Expert Opinion on Investigational Drugs
2002
Corpus ID: 24156861
Epilepsy is currently the most prevalent neurological disorder worldwide. Pharmacological therapy remains the cornerstone of…
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2002
2002
Neuroprotection Profile of the High Affinity NMDA Receptor Antagonist Conantokin-G
A. Williams
2002
Corpus ID: 28381868
Abstract : Conantokin-G (Con-G or CGX-1007), a potent NR2B subunit selective NMDA receptor antagonist, was evaluated for its…
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