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CGS 12970

Known as: CGS-12970 
National Institutes of Health

Papers overview

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Highly Cited
2001
Highly Cited
2001
Role of thromboxane in retinal microvascular degeneration in oxygen-induced retinopathy.
Microvascular degeneration is an important event in oxygen-induced retinopathy (OIR), a model of retinopathy of prematurity… 
2001
2001
2,3-Dinor-5,6-dihydro-15-F(2t)-isoprostane: a bioactive prostanoid metabolite.
15-F(2t)-isoprostane (15-F(2t)-IsoP), also termed 8-isoprostaglandin F(2alpha), is one of a series of prostanoids formed by free… 
1993
1993
Uricosuric effect of CGS‐12970, a new thromboxane synthase inhibitor
3‐Methyl‐2‐(3‐pyridyl)‐1‐indoleoctanoic acid (CGS‐12970) is a reversible thromboxane synthase inhibitor that was noted to lower… 
1991
1991
Pharmacokinetics of CGS 12970 and inihibition of thromboxane synthesis after oral administration in healthy adults
The pharmacokinetics and pharmacodynamics of biochemical effect of a selective thromboxane synthase inhibitor, CGS 12970, were… 
1990
1990
Prostanoids and hypothermic renal preservation injury.
1989
1989
Effects of the thromboxane synthesis inhibitor CGS-12970 on experimental acute renal allograft rejection.
The purpose of this study was to examine the effects and mechanisms of the selective thromboxane synthesis inhibitor CGS-12970 (3… 
1989
1989
Mechanisms responsible for inhibition of vein-graft arteriosclerosis by fish oil.
Favorable changes in lipoproteins, inhibition of platelet aggregation, reduction of serum thromboxane (TX), altered plasma… 
1986
1986
CGS-12970, a thromboxane synthetase inhibitor, limits ischemic damage following coronary artery occlusion.
: A new thromboxane synthetase inhibitor, CGS-12970, was evaluated for its ability to reduce the extension of myocardial infarct… 
1986
1986
CGS-12970, a thromboxane synthetase inhibitor, limits ischemic damage following coronary artery occlusion.
A new thromboxane synthetase inhibitor, CGS-12970, was evaluated for its ability to reduce the extension of myocardial infarct… 
1985
1985
CGS 12970: a novel, long acting thromboxane synthetase inhibitor
1 CGS 12970 is a potent selective inhibitor of human platelet thromboxane synthestase in vitro (IC50 = 12 nM). It is four orders… 
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