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CGS 12970

Known as: CGS-12970 
National Institutes of Health

Papers overview

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2001
2001
2,3-Dinor-5,6-dihydro-15-F(2t)-isoprostane: a bioactive prostanoid metabolite.
15-F(2t)-isoprostane (15-F(2t)-IsoP), also termed 8-isoprostaglandin F(2alpha), is one of a series of prostanoids formed by free… 
1993
1993
Uricosuric effect of CGS‐12970, a new thromboxane synthase inhibitor
3‐Methyl‐2‐(3‐pyridyl)‐1‐indoleoctanoic acid (CGS‐12970) is a reversible thromboxane synthase inhibitor that was noted to lower… 
1993
1993
CHRONIC THROMBOXANE SYNTHASE INHIBITION WITH CGS 12970 IN HUMAN CYCLOSPORINE NEPHROTOXICITY1
CsA nephrotoxicity in rats is associated with an increase in renal thromboxane production. Treatment with selective thromboxane… 
1991
1991
Pharmacokinetics of CGS 12970 and inihibition of thromboxane synthesis after oral administration in healthy adults
The pharmacokinetics and pharmacodynamics of biochemical effect of a selective thromboxane synthase inhibitor, CGS 12970, were… 
1990
1990
Prostanoids and hypothermic renal preservation injury.
1987
1987
Prolongation of platelet survival in hypercholesterolaemic rabbits by CGS 12970 (3-methyl-2-(3-pyridyl)-1 indoleoctanoic acid) and dazoxiben.
1987
1987
Additive Beneficial Effects of Two Inhibitors of Vasoconstrictor Mediators in Acute Myocardial Ischemia 1
Abstract A specific inhibitor of thromboxane A2 (TxA2) synthesis, CGS-12970, a new angiotensin-converting enzyme (ACE) inhibitor… 
1986
1986
CGS-12970, a thromboxane synthetase inhibitor, limits ischemic damage following coronary artery occlusion.
: A new thromboxane synthetase inhibitor, CGS-12970, was evaluated for its ability to reduce the extension of myocardial infarct… 
1986
1986
CGS-12970, a thromboxane synthetase inhibitor, limits ischemic damage following coronary artery occlusion.
A new thromboxane synthetase inhibitor, CGS-12970, was evaluated for its ability to reduce the extension of myocardial infarct… 
1985
1985
CGS 12970: a novel, long acting thromboxane synthetase inhibitor
1 CGS 12970 is a potent selective inhibitor of human platelet thromboxane synthestase in vitro (IC50 = 12 nM). It is four orders… 
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