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CGP 4540

Known as: CGP-4540 
National Institutes of Health

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amoscanate

Papers overview

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1981
1981
Anthelmintic efficacy of amoscanate (C 9333-Go/CGP 4540) against various infections in rodents, dogs and monkeys.
The anthelmintic activity of Amoscanate (C 9333-GO/CGP 4540) has been studied in experimental infections with the human hookworm… 
1981
1981
Histological changes elicited in Schistosoma japonicum infected rabbits following curative chemotherapy with 4-isothiocyano-4'-nitro-diphenylamine (C9333-Go/CGP 4540).
Highly Cited
1980
Highly Cited
1980
Schistosoma mansoni: tegumental surface alterations induced by subcurative doses of the schistosomicide amoscanate.
1979
1979
Prevention of the mutagenic activation of an antischistosomal isothiocyanate in primates by an antibiotic.
Administration of 4 nitro-4' isothiocyano-diphenylamine (CGP 4540, amoscanate) to two nonhuman primates, Macaca mulatta and Cebus… 
1978
1978
Recovery of the hepatic drug-metabolizing capacity in mice infected with Schistosoma mansoni following curative chemotherapy with the schistosomicide 4-isothiocyano-4'-nitro-diphenylamine (CGP 4540).
Treatment of mice infected with Schistosoma mansoni with a single oral dose of formulated 4-isothiocyano-4'-nitro-diphenylamine… 
1977
1977
Phase 1 tolerability and searching dose studies with 4-isothiocyanato-4'-nitrodiphenylamine (C.9333-Go/CGP 4540), a new anthelmintic.
1 Phase 1 and 2 studies were carried out in thirteen volunteers and thirty patients with hookworm anaemia with a new anthelmintic… 
1977
1977
Clinical trials of a new anthelmintic, 4-isothiocyanato-4'-nitrodiphenylamine (C.9333-Go/CGP 4540), for the cure of hookworm infection.
A new compound, 4-isothiocyanato-4'-nitrodiphenylamine (C.9333-Go/CGP 4540), was tried in 39 hospitalized patients with hookworm… 
1976
1976
Antischistosomal and some toxicological properties of a nitrodiphenylaminoisothiocyanate (C 9333-Go/CGP 4540)
A procedure to enhance the schistosomicidal effectiveness in vivo of an isothiocyanate derivative and some of its… 
1976
1976
4-isothiocyanato-4' -nitrodiphenylamine (C 9333-Go/CGP 4540) a new anthelminthic with potent antihookworm activity.
1976
1976
4-Isothiocyanato-4′-nitrodiphenylamine (C9333-Go/CGP 4540) an anthelminthic with an unusual spectrum of activity against intestinal nematodes, filariae and schistosomes
4-isothiocyanato-4′-nitrodiphenylamine was found to possess activity against intestinal nematodes in mice, against schistosomes… 
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