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CGP 4540

Known as: CGP-4540 
National Institutes of Health

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amoscanate

Papers overview

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1981
1981
Anthelmintic efficacy of amoscanate (C 9333-Go/CGP 4540) against various infections in rodents, dogs and monkeys.
The anthelmintic activity of Amoscanate (C 9333-GO/CGP 4540) has been studied in experimental infections with the human hookworm… 
1981
1981
Histological changes elicited in Schistosoma japonicum infected rabbits following curative chemotherapy with 4-isothiocyano-4'-nitro-diphenylamine (C9333-Go/CGP 4540).
1980
1980
Mutagenic activation of an antischistosomal drug by enteric Streptococcus sps in vitro and in vivo.
Previous studies have shown that a new antischistosomal drug, 4-isothiocyano-4'-nitro diphenylamine (CGP 4540, amoscanate), is… 
1979
1979
Prevention of the mutagenic activation of an antischistosomal isothiocyanate in primates by an antibiotic.
Administration of 4 nitro-4' isothiocyano-diphenylamine (CGP 4540, amoscanate) to two nonhuman primates, Macaca mulatta and Cebus… 
1979
1979
Chemotherapeutic effects of 4-isothiocyanato-4′-nitrodiphenylamine (C9333-Go/CGP 4540) on infections withNematospiroides dubius, Hymenolepis diminuta, Hymenolepis nana andSpirometra mansonoides
4-Isothiocyanato-4′-nitrodiphenylamine possessed anthelmintic activity againstNippostrongylus dubius andHymenolepis nana in mice… 
1977
1977
Phase 1 tolerability and searching dose studies with 4-isothiocyanato-4'-nitrodiphenylamine (C.9333-Go/CGP 4540), a new anthelmintic.
1 Phase 1 and 2 studies were carried out in thirteen volunteers and thirty patients with hookworm anaemia with a new anthelmintic… 
1977
1977
Clinical trials of a new anthelmintic, 4-isothiocyanato-4'-nitrodiphenylamine (C.9333-Go/CGP 4540), for the cure of hookworm infection.
A new compound, 4-isothiocyanato-4'-nitrodiphenylamine (C.9333-Go/CGP 4540), was tried in 39 hospitalized patients with hookworm… 
1976
1976
4-isothiocyanato-4' -nitrodiphenylamine (C 9333-Go/CGP 4540) a new anthelminthic with potent antihookworm activity.
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