CGP 4540

Amoscanate labelled with carbon-14 on the isothiocyanate carbon atom was prepared in an overall yield of 13% at a specific… (More)

The anthelmintic activity of Amoscanate (C 9333-GO/CGP 4540) has been studied in experimental infections with the human hookworm… (More)

New Zealand white rabbits were infected with 250 or 500 cercariae of the Philippine-Leyte strain of Schistosoma japonicum. 26… (More)

Nutzungsbedingungen Die ETH-Bibliothek ist Anbieterin der digitalisierten Zeitschriften. Sie besitzt keine Urheberrechte an den… (More)

ABSTRACT Various formulations and dosage forms of C 9333-Go/CGP 4540 have been tested against three species of schistosomes in… (More)

Administration of 4 nitro-4' isothiocyano-diphenylamine (CGP 4540, amoscanate) to two nonhuman primates, Macaca mulatta and Cebus… (More)

Treatment of mice infected with Schistosoma mansoni with a single oral dose of formulated 4-isothiocyano-4'-nitro-diphenylamine… (More)

1 Phase 1 and 2 studies were carried out in thirteen volunteers and thirty patients with hookworm anaemia with a new anthelmintic… (More)

A procedure to enhance the schistosomicidal effectiveness in vivo of an isothiocyanate derivative and some of its… (More)