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CGP 42112

Known as: CGP-42112, CGP42112 
National Institutes of Health

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CGP 42112A

Papers overview

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Highly Cited
2012
Highly Cited
2012
Angiotensin II AT2 receptor decreases AT1 receptor expression and function via nitric oxide/cGMP/Sp1 in renal proximal tubule cells from Wistar–Kyoto rats
Background: The renin–angiotensin (Ang) system controls blood pressure, in part, by regulating renal tubular sodium transport. In… 
Highly Cited
2012
Highly Cited
2012
Perinatal Nicotine Exposure Increases Vulnerability of Hypoxic–Ischemic Brain Injury in Neonatal Rats: Role of Angiotensin II Receptors
Background and Purpose— Maternal cigarette smoking increases the risk of neonatal morbidity. We tested the hypothesis that… 
Highly Cited
2009
Highly Cited
2009
Angiotensin AT2 Receptor Stimulation Causes Neuroprotection in a Conscious Rat Model of Stroke
Background and Purpose— The angiotensin II type 2 receptor (AT2R) is implicated to be neuroprotective in stroke, although this… 
Highly Cited
2002
Highly Cited
2002
AT2 Receptor-Mediated Relaxation Is Preserved After Long-Term AT1 Receptor Blockade
Abstract—Angiotensin II type 2 receptor (AT2R) stimulation may cause vasodilation per se and may contribute to the… 
Highly Cited
1999
Highly Cited
1999
AT(2) receptor stimulation enhances antihypertensive effect of AT(1) receptor antagonist in hypertensive rats.
In the present study, we investigated the role of the angiotensin type 2 (AT(2)) receptor in the regulation of blood pressure in… 
Highly Cited
1997
Highly Cited
1997
Localization of angiotensin-converting enzyme, angiotensin II, angiotensin II receptor subtypes, and vasopressin in the mouse hypothalamus
Highly Cited
1997
Highly Cited
1997
Angiotensin II stimulates secretion of endogenous ouabain from bovine adrenocortical cells via angiotensin type 2 receptors.
Angiotensin II stimulates secretion of corticosteroids and ouabain-like activity from adrenocortical cells. Distinct… 
Highly Cited
1995
Highly Cited
1995
The angiotensin AT2-receptor mediates inhibition of cell proliferation in coronary endothelial cells.
Angiotensin II (ANG II) is known to be a potent growth promoting factor for vascular smooth muscle cells and fibroblasts but… 
Highly Cited
1994
Highly Cited
1994
Angiotensin II stimulates protein tyrosine phosphatase activity through a G-protein independent mechanism.
Most of angiotensin II's (Ang II) documented effects have been attributed to the interaction of this peptide with a G-protein… 
Highly Cited
1993
Highly Cited
1993
Agonistic and antagonistic properties of angiotensin analogs at the AT2 receptor in PC12W cells
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