CGP 42112

Known as: CGP-42112, CGP42112 
 
National Institutes of Health

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CGP 42112A

Papers overview

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2012
2012
Perinatal nicotine exposure increases vulnerability of hypoxic-ischemic brain injury in neonatal rats: role of angiotensin II receptors.
BACKGROUND AND PURPOSE Maternal cigarette smoking increases the risk of neonatal morbidity. We tested the hypothesis that… (More)
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Highly Cited
2009
Highly Cited
2009
Angiotensin AT2 receptor stimulation causes neuroprotection in a conscious rat model of stroke.
BACKGROUND AND PURPOSE The angiotensin II type 2 receptor (AT(2)R) is implicated to be neuroprotective in stroke, although this… (More)
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2002
2002
AT2 receptor-mediated relaxation is preserved after long-term AT1 receptor blockade.
Angiotensin II type 2 receptor (AT2R) stimulation may cause vasodilation per se and may contribute to the antihypertensive effect… (More)
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2000
2000
Angiotensin-II subtype 2 receptor agonist (CGP-42112) inhibits catecholamine biosynthesis in cultured porcine adrenal medullary chromaffin cells.
Angiotensin II subtype 2 receptor (AT(2)-R) is abundantly expressed in adrenal medullary chromaffin cells. However, the… (More)
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1997
1997
Angiotensin II stimulates secretion of endogenous ouabain from bovine adrenocortical cells via angiotensin type 2 receptors.
Angiotensin II stimulates secretion of corticosteroids and ouabain-like activity from adrenocortical cells. Distinct… (More)
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1997
1997
CGP-42112 partially activates human monocytes and reduces their stimulation by lipopolysaccharides.
CGP 42112, a high-affinity ligand for angiotensin II AT2 receptors, binds to rat macrophage/microglia lacking AT2 receptors. Here… (More)
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Highly Cited
1996
Highly Cited
1996
Angiotensin II induction of neurite outgrowth by AT2 receptors in NG108-15 cells. Effect counteracted by the AT1 receptors.
In the present study, 3-day treatment of nondifferentiated NG108-15 cells with 100 nM angiotensin II (Ang II) induces… (More)
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Highly Cited
1996
Highly Cited
1996
Role of type 1 and type 2 angiotensin receptors in angiotensin II-induced cardiomyocyte hypertrophy.
We compared the ability of angiotensin II (Ang II) to induce hypertrophy of neonatal rat ventricular myocytes with that of… (More)
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1995
1995
Quantitative autoradiography of angiotensin II AT2 receptors with [125I]CGP 42112.
Most radiolabeled ligands for angiotensin II (Ang II) receptors do not discriminate between the AT1 and AT2 receptor subtypes… (More)
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Highly Cited
1995
Highly Cited
1995
The angiotensin AT2-receptor mediates inhibition of cell proliferation in coronary endothelial cells.
Angiotensin II (ANG II) is known to be a potent growth promoting factor for vascular smooth muscle cells and fibroblasts but… (More)
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