Skip to search formSkip to main content

CFHR4 gene

Known as: COMPLEMENT FACTOR H-RELATED 4, FHR4, CFHR4 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Genome-Wide Association Study Reveals Variants in CFH and CFHR4 Associated with Systemic Complement Activation: Implications in Age-Related Macular Degeneration.
PURPOSE To identify genetic variants associated with complement activation, which may help to select age-related macular… Expand
Is this relevant?
2012
2012
Factor H-related protein 4 activates complement by serving as a platform for the assembly of alternative pathway C3 convertase via its interaction with C3b protein.
Human complement factor H-related protein (CFHR) 4 belongs to the factor H family of plasma glycoproteins that are composed of… Expand
Is this relevant?
2012
2012
A novel hybrid CFH/CFHR3 gene generated by a microhomology-mediated deletion in familial atypical hemolytic uremic syndrome.
Genomic disorders affecting the genes encoding factor H (fH) and the 5 factor H related proteins have been described in… Expand
  • figure 1
  • table 1
  • table 2
  • figure 2
  • figure 3
Is this relevant?
2012
2012
Common genetic variants in complement genes other than CFH, CD46 and the CFHRs are not associated with aHUS
It is well established that common genetic variants in CFH, CD46 and the CFHRs are additional risk factors for the development of… Expand
Is this relevant?
2011
2011
Copy number variation in the complement factor H-related genes and age-related macular degeneration
PURPOSE To determine the contribution of copy number variation (CNV) in the regulation of complement activation (RCA) locus to… Expand
  • figure 1
  • table 1
  • table 2
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
2010
Highly Cited
2010
Association of factor H autoantibodies with deletions of CFHR1, CFHR3, CFHR4, and with mutations in CFH, CFI, CD46, and C3 in patients with atypical hemolytic uremic syndrome.
Factor H autoantibodies have been reported in approximately 10% of patients with atypical hemolytic uremic syndrome (aHUS) and… Expand
  • table 1
  • table 2
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
2010
2010
FORMULATION AND EVALUATION OF MOUTH DISINTEGRATING TABLETS OF FAMOTIDINE BY USING HIBISCUS ROSA - SINENSIS MUCILAGE AND TREATED AGAR
Mouth disintegrating tablets are those tablets which disintegrate/dissolve in the mouth with in the fraction of seconds. These… Expand
  • table 1
  • table 2
  • figure 1
  • figure 2
Is this relevant?
2005
2005
FHR-4A: a new factor H-related protein is encoded by the human FHR-4 gene
We describe a new member of the human Factor H protein family, termed Factor H-related protein 4A (FHR-4A). The corresponding… Expand
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
1999
Highly Cited
1999
Functional properties of complement factor H-related proteins FHR-3 and FHR-4: binding to the C3d region of C3b and differential regulation by heparin.
The human factor H-related proteins FHR-3 and FHR4 are members of a family of proteins related to the complement factor H. Here… Expand
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Identification of a domain in human factor H and factor H-like protein-1 required for the interaction with streptococcal M proteins.
The plasma protein factor H (FH) inhibits the alternative pathway of complement activation. Previous work has shown that FH binds… Expand
Is this relevant?