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CEP135 gene

Known as: FLJ13621, KIAA0635, centrosomal protein 135 
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
A centrosome interactome provides insight into organelle assembly and reveals a non-duplication role for Plk4
The centrosome is the major microtubule-organizing centre of many cells, best known for its role in mitotic spindle organization… 
2016
2016
WDR8 is a centriolar satellite and centriole-associated protein that promotes ciliary vesicle docking during ciliogenesis
ABSTRACT Ciliogenesis initiates at the mother centriole through a series of events that include membrane docking, displacement of… 
Highly Cited
2015
Highly Cited
2015
Conserved Molecular Interactions in Centriole-to-Centrosome Conversion
Centrioles are required to assemble centrosomes for cell division and cilia for motility and signalling. New centrioles assemble… 
Highly Cited
2014
Highly Cited
2014
Multisite phosphorylation of C-Nap1 releases it from Cep135 to trigger centrosome disjunction
ABSTRACT During mitotic entry, centrosomes separate to establish the bipolar spindle. Delays in centrosome separation can perturb… 
2014
2014
The Centriolar Protein Bld10/Cep135 Is Required to Establish Centrosome Asymmetry in Drosophila Neuroblasts
2013
2013
Abnormal centrosomal structure and duplication in Cep135-deficient vertebrate cells
Gene targeting was used to ablate Cep135, a component of the centriolar cartwheel, in chicken DT40 cells. Cep135-deficient cells… 
Highly Cited
2012
Highly Cited
2012
3D-structured illumination microscopy provides novel insight into architecture of human centrosomes
Summary Centrioles are essential for the formation of cilia and flagella. They also form the core of the centrosome, which… 
Highly Cited
2012
Highly Cited
2012
A truncating mutation of CEP135 causes primary microcephaly and disturbed centrosomal function.
2004
2004
Interaction of Cep135 with a p50 dynactin subunit in mammalian centrosomes.
Cep135 is a 135-kDa, coiled-coil centrosome protein important for microtubule organization in mammalian cells [Ohta et al., 2002… 
Highly Cited
2002
Highly Cited
2002
Characterization of Cep135, a novel coiled-coil centrosomal protein involved in microtubule organization in mammalian cells
By using monoclonal antibodies raised against isolated clam centrosomes, we have identified a novel 135-kD centrosomal protein… 
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