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CEP 751
Known as:
CEP-751
, CEP751
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (1)
Carbazoles
KT6587
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
Phase I clinical trial of CEP-2563 dihydrochloride, a receptor tyrosine kinase inhibitor, in patients with refractory solid tumors
S. Undevia
,
N. Vogelzang
,
A. Mauer
,
L. Janisch
,
S. Mani
,
M. Ratain
Investigational new drugs
2004
Corpus ID: 38403894
CEP-2563 dihydrochloride (CEP-2563) is a soluble lysinyl-β-alanyl ester of CEP-751, a potent inhibitor of the trk family of…
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Highly Cited
2000
Highly Cited
2000
Rational basis for Trk inhibition therapy for prostate cancer
A. Weeraratna
,
J. Arnold
,
Dan J. George
,
A. DeMarzo
,
J. Isaacs
The Prostate
2000
Corpus ID: 23742985
Prostatic cancer cells are lethal because they acquire the ability to activate survival pathways that do not require androgenic…
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Highly Cited
1999
Highly Cited
1999
Antitumor activity of CEP-751 (KT-6587) on human neuroblastoma and medulloblastoma xenografts.
A. Evans
,
K. Kisselbach
,
+4 authors
G. Brodeur
Clinical Cancer Research
1999
Corpus ID: 15553498
Neuroblastoma (NBL) and medulloblastoma (MBL) are tumors of the neuroectoderm that occur in children. NBL and MBL express Trk…
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Highly Cited
1997
Highly Cited
1997
CEP‐751 inhibits trk receptor tyrosine kinase activity in vitro and exhibits anti‐tumor activity
A. M. Camoratto
,
J. Jani
,
+7 authors
C. Dionne
International Journal of Cancer
1997
Corpus ID: 22786330
The present report describes the in vitro and in vivo profile of CEP‐751, a novel receptor tyrosine kinase inhibitor. CEP‐751 at…
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