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CELF4 gene

Known as: BRUNO-LIKE 4, CELF4, BRUNOL4 
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
CELF4 Variant and Anthracycline-Related Cardiomyopathy: A Children's Oncology Group Genome-Wide Association Study.
PURPOSE Interindividual variability in the dose-dependent association between anthracyclines and cardiomyopathy suggests that… 
Highly Cited
2013
Highly Cited
2013
Development of GMDR-GPU for Gene-Gene Interaction Analysis and Its Application to WTCCC GWAS Data for Type 2 Diabetes
Although genome-wide association studies (GWAS) have identified a significant number of single-nucleotide polymorphisms (SNPs… 
2013
2013
Aberrant sodium channel activity in the complex seizure disorder of Celf4 mutant mice
•  Inappropriate electrochemical signalling between neurons is a central problem in epilepsy. Only a fraction of all heritable… 
Highly Cited
2012
Highly Cited
2012
CELF4 Regulates Translation and Local Abundance of a Vast Set of mRNAs, Including Genes Associated with Regulation of Synaptic Function
RNA–binding proteins have emerged as causal agents of complex neurological diseases. Mice deficient for neuronal RNA–binding… 
2011
2011
Etiology of a genetically complex seizure disorder in Celf4 mutant mice
Mice deficient for the gene encoding the RNA‐binding protein CELF4 (CUGBP, ELAV‐like family member 4) have a complex seizure… 
Highly Cited
2009
Highly Cited
2009
MBNL and CELF proteins regulate alternative splicing of the skeletal muscle chloride channel CLCN1
The expression and function of the skeletal muscle chloride channel CLCN1/ClC-1 is regulated by alternative splicing. Inclusion… 
Highly Cited
2005
Highly Cited
2005
Identification of CELF splicing activation and repression domains in vivo
CUG-BP and ETR-3 like factor (CELF) proteins are regulators of pre-mRNA alternative splicing. We created a series of truncation… 
2004
2004
ETR-3 and CELF4 protein domains required for RNA binding and splicing activity in vivo.
Members of the CUG-BP and ETR-3 like factor (CELF) protein family bind within conserved intronic elements (called MSEs) flanking… 
2002
2002
Identification and characterization of murine Brunol4, a new member of the elav/bruno family
RNA-binding proteins are involved in post-transcriptional processes like mRNA stabilization, post-transcriptional modification… 
Highly Cited
2001
Highly Cited
2001
The CELF Family of RNA Binding Proteins Is Implicated in Cell-Specific and Developmentally Regulated Alternative Splicing
ABSTRACT Alternative splicing of cardiac troponin T (cTNT) exon 5 undergoes a developmentally regulated switch such that exon… 
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