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CELF1 gene

Known as: NUCLEAR POLYADENYLATED RNA-BINDING PROTEIN, 50-KD, NAPOR, hNab50 
National Institutes of Health

Papers overview

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2020
2020
The cataract-linked RNA-binding protein Celf1 post-transcriptionally controls the spatiotemporal expression of the key homeodomain transcription factors Pax6 and Prox1 in lens development
The homeodomain transcription factors (TFs) Pax6 (OMIM: 607108) and Prox1 (OMIM: 601546) critically regulate gene expression in… 
2017
2017
The CELF1 RNA-Binding Protein Regulates Decay of Signal Recognition Particle mRNAs and Limits Secretion in Mouse Myoblasts
We previously identified several mRNAs encoding components of the secretory pathway, including signal recognition particle (SRP… 
Highly Cited
2015
Highly Cited
2015
Competition between RNA-binding proteins CELF1 and HuR modulates MYC translation and intestinal epithelium renewal
ELAV-like family member 1, or CELF1, competes with another RNA-binding protein, HuR, to modulate MYC translation and plays an… 
2015
2015
CUGBP1 promotes cell proliferation and suppresses apoptosis via down-regulating C/EBPα in human non-small cell lung cancers
CUGBP1, which is involved in posttranscriptional regulatory networks, may control cell growth, activation and differentiation… 
Highly Cited
2011
Highly Cited
2011
p21WAF1/CIP1 Upregulation through the Stress Granule-Associated Protein CUGBP1 Confers Resistance to Bortezomib-Mediated Apoptosis
Background p21WAF1/CIP1 is a well known cyclin-dependent kinase inhibitor induced by various stress stimuli. Depending on the… 
2011
2011
CUG-binding protein represses translation of p27Kip1 mRNA through its internal ribosomal entry site
The cyclin dependent kinase inhibitor p27Kip1 plays an important role in controlling the eukaryotic cell cycle. The 5… 
2010
2010
Analysis of MTMR1 expression and correlation with muscle pathological features in juvenile/adult onset myotonic dystrophy type 1 (DM1) and in myotonic dystrophy type 2 (DM2).
Highly Cited
2008
Highly Cited
2008
The RNA-binding Protein CUGBP1 Regulates Stability of Tumor Necrosis Factor mRNA in Muscle Cells
Type I myotonic dystrophy (DM1) is caused by a triplet repeat expansion in the 3′-untranslated region (UTR) of the dystrophia… 
2007
2007
A Ferritin-responsive Internal Ribosome Entry Site Regulates Folate Metabolism*
Cytoplasmic serine hydroxymethyltransferase (cSHMT) enzyme levels are elevated by the expression of the heavy chain ferritin (H… 
2007
2007
CUGBP1 is required for IFNbeta-mediated induction of dominant-negative CEBPbeta and suppression of SIV replication in macrophages.
Productive HIV replication in the CNS occurs very early after infection, yet HIV-associated cognitive disorders do not typically… 
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