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CDX1 gene

Known as: caudal type homeobox 1, CAUDAL-TYPE HOMEOBOX TRANSCRIPTION FACTOR 1, CDX1 
This gene is involved in gene expression in the intestine.
National Institutes of Health

Related topics

Related topics

9 relations
CDX1 protein, humanCDX4 geneCell Differentiation processHomo sapiens

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Cdx4 is a direct target of the canonical Wnt pathway.
Highly Cited
2004
Highly Cited
2004
Down-regulation of a gastric transcription factor, Sox2, and ectopic expression of intestinal homeobox genes, Cdx1 and Cdx2: inverse correlation during progression from gastric/intestinal-mixed to…
Purpose The molecular mechanisms underlying the development of intestinal metaplasia (IM) of the human stomach have yet to be… 
Highly Cited
2004
Highly Cited
2004
Cdx1 Autoregulation Is Governed by a Novel Cdx1-LEF1 Transcription Complex
ABSTRACT The Cdx1 gene product is essential for normal anterior-posterior vertebral patterning. Expression of Cdx1 is regulated… 
Highly Cited
2002
Highly Cited
2002
Cdx1 and Cdx2 have overlapping functions in anteroposterior patterning and posterior axis elongation.
Mouse Cdx and Hox genes presumably evolved from genes on a common ancestor cluster involved in anteroposterior patterning… 
Highly Cited
2002
Highly Cited
2002
Ectopic expression of homeodomain protein CDX2 in intestinal metaplasia and carcinomas of the stomach.
Highly Cited
2002
Highly Cited
2002
Expression of homeobox gene CDX2 precedes that of CDX1 during the progression of intestinal metaplasia
Background. The CDX1 and CDX2 genes are intestinal transcription factors that may be involved in the regulation of proliferation… 
Highly Cited
2000
Highly Cited
2000
Retinoic Acid Regulation of Cdx1: an Indirect Mechanism for Retinoids and Vertebral Specification
ABSTRACT Retinoic acid (RA) is required for diverse developmental programs, including vertebral specification. Both RA receptor… 
Highly Cited
1997
Highly Cited
1997
CDX1 protein expression in normal, metaplastic, and neoplastic human alimentary tract epithelium.
BACKGROUND & AIMS CDX1 is an intestine-specific transcription factor expressed early in intestinal development that may be… 
Highly Cited
1997
Highly Cited
1997
Molecular cloning, sequencing and expression of the mRNA encoding human Cdx1 and Cdx2 homeobox. Down‐regulation of Cdx1 and Cdx2 mRNA expression during colorectal carcinogenesis
Defining the molecular mechanisms involved in cancer formation and progression is still a major challenge in colorectal‐cancer… 
Highly Cited
1995
Highly Cited
1995
Disruption of the murine homeobox gene Cdx1 affects axial skeletal identities by altering the mesodermal expression domains of Hox genes
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