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CDR3 Spectratyping

Known as: Complementary Determining Region 3 Spectratyping 
A laboratory procedure that analyzes the genetic profile of the T-cell receptor variable complementary determining region 3 (CDR3) for an individual… 
National Institutes of Health

Papers overview

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2006
2006
Clonotypic analysis of cerebrospinal fluid T cells during disease exacerbation and remission in a patient with multiple sclerosis
2003
2003
CDR3 spectratyping analysis of the T cell receptor repertoire in Guillain–Barré and Fisher syndromes
2003
2003
T-cell receptor repertoire in healthy Sardinian subjects.
2001
2001
Two‐step activation of T cells, clonal expansion and subsequent Th1 cytokine production, is essential for the development of clinical autoimmune encephalomyelitis
Lewis rats immunized with guinea pig myelin basic protein (GPBP) emulsified with incomplete Freund's adjuvant (IFA) do not… 
2001
2001
Molecular correlates in AIDS patients following antiretroviral therapy: diversified T‐cell receptor repertoires and in vivo control of cytomegalovirus replication
1 Department of Immunology and 2 The Kobler Centre, Chelsea and Westminster Hospital, and 3 Royal Free Hospital and University… 
2000
2000
Delayed recovery of CDR3 complexity of the T-cell receptor-beta chain in recipients of allogeneic bone marrow transplants who had virus-associated interstitial pneumonia: monitor of T-cell function…
BACKGROUND In the T-cell receptor (TCR)-beta chain, complementary-determining region 3 (CDR3) contains specific peptide sequences… 
2000
2000
Patterns of CD8 T cell clonal dominance in response to change in antiretroviral therapy in HIV-infected children
ObjectiveTo examine the influence of change in antiretroviral therapy (ART) on patterns of CD8 T cell clonal dominance in HIV… 
2000
2000
Characterization of T cell receptor associated with the development of P2 peptide-induced autoimmune neuritis
2000
2000
The Virus-Specific and Allospecific Cytotoxic T-Lymphocyte Response to Lymphocytic Choriomeningitis Virus Is Modified in a Subpopulation of CD8+ T Cells Coexpressing the Inhibitory Major…
ABSTRACT The role of negatively signaling NK cell receptors of the Ly49 family on the specificity of the acute CD8+ cytotoxic T… 
1998
1998
Persistent expression of experimental autoimmune encephalomyelitis (EAE)-specific Vbeta8.2 TCR spectratype in the central nervous system of rats with chronic relapsing EAE.
Monitoring the TCR repertoire is indispensable for the assessment of T cell-associated autoimmune diseases and subsequent TCR… 
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