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CDH4 protein, human

Known as: Retinal Cadherin, R-cadherin protein, human, Cadherin 4 
Cadherin-4 (916 aa, ~100 kDa) is encoded by the human CDH4 gene. This protein is involved in both cell adhesion and retinal development.
National Institutes of Health

Related topics

Related topics

13 relations
BrainCDH4 geneCadherin DomainCell Adhesion

Broader (1)

R-cadherin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Expression of Cadherin Superfamily Genes in Brain Vascular Development
Cadherins are Ca2+-dependent cell adhesion molecules that are important in vertebrate nervous system development. We identified… 
Review
2003
Review
2003
Cadherin switching in ovarian cancer progression
The roles of the cadherins in the progression of ovarian cancer to the late stages of the disease state when malignant cells have… 
Highly Cited
2000
Highly Cited
2000
Mutation analysis of cadherin-4 reveals amino acid residues of EC1 important for the structure and function.
To clarify the structural basis of the cell adhesion activity of cadherins, we examined the effects of point mutations of well… 
2000
2000
Lateral clustering of cadherin-4 without homophilic interaction: possible involvement in the concentration process at cell-cell adhesion sites as well as in the cell adhesion activity.
It is thought that the concentration of classic cadherins at cell-cell adhesion sites is essential for generating strong cell… 
Highly Cited
2000
Highly Cited
2000
Complex cadherin expression in human prostate cancer cells
Changes in cell‐cell interactions are critical in the process of cancer progression. Likewise, it has been shown that loss of… 
Highly Cited
1994
Highly Cited
1994
Characterization of cadherin-4 and cadherin-5 reveals new aspects of cadherins.
Several properties of cadherin-4 and cadherin-5 were characterized by using the cDNA transfection approach. The proteins of both… 
Highly Cited
1991
Highly Cited
1991
Diversity of the cadherin family: evidence for eight new cadherins in nervous tissue.
To examine the diversity of the cadherin family, we isolated cDNAs from brain and retina cDNA preparations with the aid of… 
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