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CD45RC

Known as: CD45RC Antigen, Receptor-Type Tyrosine-Protein Phosphatase C Isoform CD45RC 
CD45RC is encoded by the human PTPRC gene. This protein plays a role in both lymphocyte activity and protein dephosphorylation. It is an isoform of… 
National Institutes of Health

Related topics

Related topics

11 relations
DephosphorylationEnzyme GeneEsterase GeneHydrolase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Transient antibody targeting of CD45RC induces transplant tolerance and potent antigen-specific regulatory T cells.
Rat and human CD4+ and CD8+ Tregs expressing low levels of CD45RC have strong immunoregulatory properties. We describe here that… 
2004
2004
Functional and Genetic Analysis of Two CD8 T Cell Subsets Defined by the Level of CD45RC Expression in the Rat1
Differential cytokine production by T cells plays an important role in the outcome of the immune response. We show that the level… 
Review
2001
Review
2001
Induction of autoimmunity through bystander effects. Lessons from immunological disorders induced by heavy metals.
Autoreactive T cells exist in healthy individuals and represent a potential reservoir of pathogenic effectors which, when… 
2000
2000
Single expression of CD45RC and RT6 in correlation with T-helper 1 and T-helper 2 cytokine patterns in the rat.
Previous studies involving the function and development of peripheral T cells have proposed that, in the rat, CD4(+)CD45RC(+)RT6… 
Review
1998
Review
1998
Overview of the Second International Workshop to define swine cluster of differentiation (CD) antigens.
1998
1998
Definition of the specificity of monoclonal antibodies against porcine CD45 and CD45R: report from the CD45/CD45R and CD44 subgroup of the Second International Swine CD Workshop.
1995
1995
Migration pathways of CD4 T cell subsets in vivo: the CD45RC- subset enters the thymus via α4 integrin-VCAM-1 interaction
The present investigation examines the localization and migration of purified T cell subsets in comparison with B cells, CD8 T… 
1994
1994
Human CD45RC specificity. A novel marker for T cells at different maturation and activation stages.
The different isoforms of CD45 seem to play an important role in thymocyte maturation and T cell activation and function. To… 
1993
1993
Rapid re‐expression of CD45RC on rat CD4 T cells in vitro correlates with a change in function
Rat CD4+ T cells are divided phenotypically by the anti‐CD45RC monoclonal antibody OX22 into subsets with contrasting functions… 
Highly Cited
1992
Highly Cited
1992
Functional maturation of recent thymic emigrants in the periphery: Development of alloreactivity correlates with the cyclic expression of CD45RC isoforms
The transition from fully developed CD4+CD8− single‐positive (SP) thymocytes into fully mature recirculating peripheral T cells… 
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