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CD4-IgG

Known as: CD4 IgG 
National Institutes of Health

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CD4 Immunoadhesins

Papers overview

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2010
2010
CD 4-IgG Binding Threshold for Inactivation of Human Immunodeficiency Virus Type 1
The stoichiometry of human immunodeficiency virus type 1 (HIV-1) inactivation by soluble receptor CD4-IgG hybrid dimers (CD4-IgG… 
2000
2000
Gene transfer of anti-gp41 antibody and CD4 immunoadhesin strongly reduces the HIV-1 load in humanized severe combined immunodeficient mice
ObjectiveTo study the anti-HIV-1 effects of the delivery of anti-gp41 monoclonal antibody (mAb) and soluble CD4 (sCD4… 
1997
1997
Current Status of CD4-Based Therapies for Prophylaxis and Treatment of HIV Infection
SummaryCD4 is a member of the immunoglobulin superfamily. It is usually found as a surface glycoprotein on mature circulating T… 
1997
1997
Human Immunodeficiency Virus Type 1 Mutants That Escape Neutralization by Human Monoclonal Antibody IgG 1 b 12
IgG1b12, a human monoclonal antibody (MAb) to an epitope overlapping the CD4-binding site on gp120, has broad and potent… 
1996
1996
CD4-IgG binding threshold for inactivation of human immunodeficiency virus type 1.
The stoichiometry of human immunodeficiency virus type 1 (HIV-1) inactivation by soluble receptor CD4-IgG hybrid dimers (CD4-IgG… 
1996
1996
Altered CD4 interactions of HIV type 1 LAI variants selected for the capacity to induce membrane fusion in the presence of a monoclonal antibody to domain 2 of CD4.
We selected HIV-1-LAI variants with the ability to induce syncytium formation of C8166 cells in the presence of a monoclonal… 
1996
1996
Design and application of a low-temperature Peltier-cooling microscope stage.
A light microscopy system has been designed for freezing and lyophilization studies of protein pharmaceuticals. The system… 
1994
1994
Modification of CD4 immunoadhesin with monomethoxypoly(ethylene glycol) aldehyde via reductive alkylation.
CD4 immunoadhesin (CD4-IgG) is a chimeric glycoprotein molecule comprised of the gp120-binding portion of human CD4 fused to the… 
1993
1993
Effect of a recombinant CD4-IgG on in vitro T helper cell function: data from a phase I/II study of patients with AIDS.
Ten patients with AIDS were enrolled in a phase I/II protocol of recombinant CD4-IgG (rCD4-IgG) treatment. Patients' peripheral… 
1992
1992
[Recombinant CD4-IgG in the treatment of AIDS and correlated syndromes: 1st stage of the study].
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