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CD2AP gene

Known as: CD2AP, CAS LIGAND WITH MULTIPLE SH3 DOMAINS, CD2-ASSOCIATED PROTEIN 
This gene plays a role in both protein-protein interactions and cell division.
National Institutes of Health

Related topics

Related topics

4 relations
CD2-associated proteinCD2AP protein, humanCytokinesisprotein protein interaction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Diabetic conditions downregulate the expression of CD2AP in podocytes via PI3‐K/Akt signalling
Proteinuria is typically accompanied by structural and compositional changes of the foot processes and of the slit diaphragms… 
2011
2011
Role for a Cindr–Arf6 axis in patterning emerging epithelia
The fly pupal eye is used to explore dArf6 activity regulated by the Arf GTPase–activating proteins (ArfGAPs) dAsap and dArfGAP3… 
Review
2011
Review
2011
Molecular and Genetic Basis of Inherited Nephrotic Syndrome
Nephrotic syndrome is an heterogeneous disease characterized by increased permeability of the glomerular filtration barrier for… 
2010
2010
Podocyte-specific overexpression of GLUT1 surprisingly reduces mesangial matrix expansion in diabetic nephropathy in mice.
Increased expression of the facilitative glucose transporter, GLUT1, leads to glomerulopathy that resembles diabetic nephropathy… 
2009
2009
TbetaRI independently activates Smad- and CD2AP-dependent pathways in podocytes.
TGF-beta regulates differentiation, growth, and apoptosis of podocytes and mediates podocyte depletion in glomerulosclerosis. TGF… 
2008
2008
CD2AP and Cbl-3/Cbl-c Constitute a Critical Checkpoint in the Regulation of Ret Signal Transduction
The glial cell line-derived neurotrophic factor (GDNF) family ligands (GFLs) are critical for nervous system development and… 
2006
2006
Glomerular expression of transforming growth factor–β (TGF-β) isoforms in mice lacking CD2-associated protein
Mice lacking CD2-associated protein (CD2AP−/−) develop glomerular lesions resembling human focal segmental glomerulosclerosis… 
2004
2004
Podocin and nephrotic syndrome: implications for the clinician.
Idiopathic nephrotic syndrome (INS) is the most frequent glomerular disease in childhood. Most of the children respond to… 
Review
2003
Review
2003
Molecular structure-function relationship in the slit diaphragm.
The past 5 years have witnessed an exponential increase in our understanding of the structure and function of the glomerular slit… 
2002
2002
Ruk is ubiquitinated but not degraded by the proteasome.
The regulator of ubiquitous kinase (Ruk) protein, also known as CIN85 or SETA, is an adaptor-type protein belonging to the CD2AP… 
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