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CD248 gene

Known as: ENDOSIALIN, CD248, CD248 molecule 
This gene may play a role in angiogenesis.
National Institutes of Health

Related topics

Related topics

4 relations
Angiogenic ProcessCD248 protein, human

Narrower (1)

CD248 wt Allele

Broader (1)

Genes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Characterization of the first fully human anti-TEM1 scFv in models of solid tumor imaging and immunotoxin-based therapy
Tumor endothelial marker 1 (TEM1) has been identified as a novel surface marker upregulated on the blood vessels and stroma in… 
2016
2016
Novel antibody probes for the characterization of endosialin/TEM-1
Endosialin (Tumor Endothelial Marker-1 (TEM-1), CD248) is primarily expressed on pericytes of tumor-associated microvasculature… 
2015
2015
CD248/Endosialin: A Novel Pericyte Target in Renal Fibrosis
pericyte to myofibroblast transition and CKD. CD248 was first identified as a tumor vascular endothelial antigen in the early… 
2013
2013
Facile immunotargeting of nanoparticles against tumor antigens using site-specific biotinylated antibody fragments.
Nanotechnology is actively being developed for preclinical and clinical oncology applications. Nanoparticle-based immunotargeting… 
2012
2012
Cdc5-Dependent Asymmetric Localization of Bfa1 Fine-Tunes Timely Mitotic Exit
In budding yeast, the major regulator of the mitotic exit network (MEN) is Tem1, a GTPase, which is inhibited by the GTPase… 
Review
2011
Review
2011
Endosialin: a novel malignant cell therapeutic target for neuroblastoma.
Endosialin emerged recently as a potential therapeutic target for sarcoma. Since some sarcoma subtypes, such as Ewing's sarcoma… 
2010
2010
No PDGF receptor signal in pericytes without endosialin?
Commentary to: Endosialin/TEM-1/CD248 regulates pericyte proliferation through PDGF receptor signaling Brian Tomkowicz, Kathy… 
2006
2006
Modulation of effector affinity by hinge region mutations also modulates switching activity in an engineered allosteric TEM1 beta-lactamase switch.
Highly Cited
1998
Highly Cited
1998
Morphogenesis beyond Cytokinetic Arrest in Saccharomyces cerevisiae
The budding yeast lyt1 mutation causes cell lysis. We report here that lyt1 is an allele of cdc15, a gene which encodes a protein… 
1996
1996
New marker for blood vessels in human ovarian and endometrial cancers.
Angiogenesis plays a critical role in tumor biology and may someday be a target for novel therapeutic interventions. To date… 
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