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CD20-targeted Polypeptide TRU-015

Known as: TRU-015 
A proprietary antibody-based single-chain polypeptide with B cell-depleting activity. Significantly smaller than a whole antibody, CD20-targeted… 
National Institutes of Health

Related topics

Related topics

1 relation
Human B-Lymphocyte Antigen CD20, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
FRI0244 Clinical efficacy of 2 dosing regimens of tru-015, a b cell-depleting agent, in subjects with active seropositive rheumatoid arthritis compared with placebo on a stable background of…
Background In a Phase 2b double-blind, placebo-controlled randomized clinical trial, 222 subjects with seropositive, active… 
2011
2011
Therapeutic and diagnostic methods using anti-cd200 antibody
1. A method of treating a human suffering from cancer comprising administering to a human anti-CD200 antibody or CD200-binding… 
Review
2009
Review
2009
Neue Anti-B-Zell-Strategien für die Therapie rheumatischer Erkrankungen
  • Dr. I.H. Tarner
  • Zeitschrift für Rheumatologie (Print)
  • 2009
  • Corpus ID: 25120515
ZusammenfassungDer klinische Erfolg der Depletierung von B-Zellen durch den Anti-CD20-Antikörper Rituximab hat eine neue Ära in… 
2009
2009
Ingénierie de charpentes protéiques comme alternative aux anticorps : De la recherche au développement clinique
D’importants progres realises durant les deux dernieres decennies dans le domaine du genie moleculaire des proteines ont permis l… 
2008
2008
Gateways to clinical trials.
Gateways to Clinical Trials are a guide to the most recent clinical trials in current literature and congresses. The data in the… 
2007
2007
Gateways to clinical trials.
Agomelatine, AGRO-100, AIDSVAX gp120 B/E, alfimeprase, aliskiren fumarate, ALVAC vCP1452, alvocidib hydrochloride, ambrisentan… 
2007
2007
Autoimmunity P 7 Disrupting Mer receptor tyrosine kinase expression prevents autoimmune chronic graft-versus-host disease
Background IL-21 is secreted by activated T cells and modulates immune cell functions with both proinflammatory and anti… 
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