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CD-expressing Bifidobacterium APS001F

Known as: APS001F 
A recombinant anaerobic bacterium, Bifidobacterium longum, encoding the cytosine deaminase (CD) gene with potential antineoplastic adjuvant activity… 
National Institutes of Health

Papers overview

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2010
2010
Abstract 5530: A novel bacterial anticancer treatment modality targeting hypoxic solid tumors as an enzyme-prodrug using non-pathogenicBifidobacterium longumexpressing cytosine deaminase
Solid tumors generally exhibit anaerobic or hypoxic regions compared with normal tissues, which causes a potential therapeutic… 
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