CCZ1 gene

Known as: CGI-43, CCZ1 homolog, vacuolar protein trafficking and biogenesis associated, CCZ1 
 
National Institutes of Health

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BRAT1 geneGET4 gene

Papers overview

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2014
2014
Activation of the Rab7 GTPase by the MON1-CCZ1 Complex Is Essential for PVC-to-Vacuole Trafficking and Plant Growth in Arabidopsis.
Rab GTPases serve as multifaceted organizers during vesicle trafficking. Rab7, a member of the Rab GTPase family, has been shown… (More)
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2014
2014
The Mon1-Ccz1 GEF activates the Rab7 GTPase Ypt7 via a longin-fold-Rab interface and association with PI3P-positive membranes.
To function in fusion and signaling, Rab GTPases need to be converted into their active GTP form. We previously identified the… (More)
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2011
2011
CCZ1, MON1 and YPT7 genes are involved in pexophagy, the Cvt pathway and non-specific macroautophagy in the methylotrophic yeast Pichia pastoris.
Orthologues of Saccharomyces cerevisiae CCZ1, MON1 and YPT7 genes in the methylotrophic yeast, Pichia pastoris, have been… (More)
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Highly Cited
2010
Highly Cited
2010
The Mon1-Ccz1 Complex Is the GEF of the Late Endosomal Rab7 Homolog Ypt7
Rab GTPases coordinate membrane fusion reactions [1]. Rab-GDP requires a guanine nucleotide exchange factor (GEF) for its… (More)
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Highly Cited
2010
Highly Cited
2010
Identification of two evolutionarily conserved genes regulating processing of engulfed apoptotic cells
Engulfment of apoptotic cells occurs throughout life in multicellular organisms. Impaired apoptotic cell clearance (due to… (More)
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2010
2010
Early origin of genes encoding subunits of biogenesis of lysosome-related organelles complex-1, -2 and -3.
Biogenesis of lysosome-related organelles complex (BLOC)-1, -2 and -3 are three multi-subunit protein complexes that are… (More)
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Highly Cited
2003
Highly Cited
2003
Yeast homotypic vacuole fusion requires the Ccz1–Mon1 complex during the tethering/docking stage
The function of the yeast lysosome/vacuole is critically linked with the morphology of the organelle. Accordingly, highly… (More)
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Highly Cited
2002
Highly Cited
2002
The Ccz1-Mon1 protein complex is required for the late step of multiple vacuole delivery pathways.
Mon1 and Ccz1 were identified from a gene deletion library as mutants defective in the vacuolar import of aminopeptidase I (Ape1… (More)
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2001
2001
The Ccz1 protein interacts with Ypt7 GTPase during fusion of multiple transport intermediates with the vacuole in S. cerevisiae.
Previously we have shown that the Saccharomyces cerevisiae CCZ1 (YBR131w) gene encodes a protein involved in protein trafficking… (More)
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1999
1999
Disruption of six novel yeast genes located on chromosome II reveals one gene essential for vegetative growth and two required for sporulation and conferring hypersensitivity to various chemicals.
A PCR-based method for targeted gene deletion by kanMX4 module was used to construct complete deletion mutants of six individual… (More)
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