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ABSTRACT Introduction: The age-standardized death rate from diabetic kidney disease increased by 106% from 1990 to 2013… Expand BACKGROUND
Patients with type 2 diabetes and nephropathy have high cardiorenal morbidity and mortality despite optimum treatment… Expand Chemokine (C-C motif) receptor 2 (CCR2) is central for the migration of monocytes into inflamed tissues. The novel CCR2… Expand OBJECTIVE
CCR2 inhibition has produced promising experimental and clinical anti-hyperglycemic effects. These results support the… Expand Study background: Inflammatory macrophages expressing the C-C chemokine receptor 2 (CCR2) accumulate in adipose tissue and… Expand The following manuscript was published as a Fast Forward article on February 29, 2012: Sullivan TJ, Dairaghi DJ, Krasinski A… Expand