CCG-203971

 

Topic mentions per year

Topic mentions per year

2013-2017
02420132017

Papers overview

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2017
2017
We recently reported the development of a novel inhibitor of Rho-mediated gene transcription (1, CCG-203971) that is efficacious… (More)
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2017
2017
Melanoma is the most dangerous form of skin cancer with the majority of deaths arising from metastatic disease. Evidence… (More)
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2017
2017
The myocardin-related transcription factor/serum response factor (MRTF/SRF) pathway represents a promising therapeutic target to… (More)
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2017
2017
Background and Aims Intestinal fibrosis is a frequent complication in Crohn's disease [CD]. The mouse Salmonella typhimurium… (More)
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2016
2016
Transforming growth factor (TGF)-β-induced epithelial-mesenchymal transition (EMT) leads to the formation of ocular fibrotic… (More)
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2015
2015
Myofibroblasts are crucial to the pathogenesis of tissue fibrosis. Their formation of stress fibers results in the release of… (More)
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2015
2015
CCG-1423 suppresses several pathological processes including cancer cell migration, tissue fibrosis, and the development of… (More)
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2014
2014
BACKGROUND Ras homolog gene family, member A (RhoA)/Rho-associated coiled-coil forming protein kinase signaling is a key pathway… (More)
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2014
2014
Systemic sclerosis (SSc), or scleroderma, similar to many fibrotic disorders, lacks effective therapies. Current trials focus on… (More)
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Review
2013
Review
2013
CCG-1423 (1) is a novel inhibitor of Rho/MKL1/SRF-mediated gene transcription that inhibits invasion of PC-3 prostate cancer… (More)
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