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CCAR2 gene

Known as: CCAR2, cell cycle and apoptosis regulator 2, KIAA1967 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Genes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2017
Highly Cited
2017
A comparative study of anti-aging properties and mechanism: resveratrol and caloric restriction
Resveratrol and caloric restriction (CR) are the powerful therapeutic options for anti-aging. Here, their comparative effect on… 
Highly Cited
2012
Highly Cited
2012
DBIRD integrates alternative mRNA splicing with RNA polymerase II transcript elongation
Alternative messenger RNA splicing is the main reason that vast mammalian proteomic complexity can be achieved with a limited… 
Highly Cited
2012
Highly Cited
2012
Role of Deleted in Breast Cancer 1 (DBC1) Protein in SIRT1 Deacetylase Activation Induced by Protein Kinase A and AMP-activated Protein Kinase*
Background: DBC1 is a key regulator of SIRT1 activity, although it is unknown how the SIRT1-DBC1 interaction is regulated… 
Highly Cited
2011
Highly Cited
2011
Peptide switch is essential for Sirt1 deacetylase activity.
Highly Cited
2010
Highly Cited
2010
HDAC3 Is Negatively Regulated by the Nuclear Protein DBC1*
HDAC3 is a member of the class I histone deacetylase family that regulates gene expression by deacetylation of histones and non… 
Highly Cited
2009
Highly Cited
2009
Distinct HIC1-SIRT1-p53 loop deregulation in lung squamous carcinoma and adenocarcinoma patients.
A HIC1-SIRT1-p53 circular loop in which hypermethylation in cancer 1 (HIC1) represses the transcription of SIRT1 that… 
Highly Cited
2009
Highly Cited
2009
Deleted in Breast Cancer 1, a Novel Androgen Receptor (AR) Coactivator That Promotes AR DNA-binding Activity*
Androgen receptor (AR) plays a critical role in development and maintenance of male reproductive functions and the etiology of… 
Highly Cited
2009
Highly Cited
2009
Identification and Characterization of a Novel Nuclear Protein Complex Involved in Nuclear Hormone Receptor-mediated Gene Regulation*
NRC/NCoA6 plays an important role in mediating the effects of ligand-bound nuclear hormone receptors as well as other… 
Highly Cited
2008
Highly Cited
2008
Genes implicated in multiple sclerosis pathogenesis from consilience of genotyping and expression profiles in relapse and remission
BackgroundMultiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system (CNS). Although the… 
Highly Cited
2005
Highly Cited
2005
Caspase-dependent processing activates the proapoptotic activity of deleted in breast cancer-1 during tumor necrosis factor-alpha-mediated death signaling
Deleted in breast cancer-1 (DBC-1) was initially cloned from a homozygously deleted region in breast and other cancers on human… 
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