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CBX8 gene

Known as: HPC3, chromobox 8, Pc class 3 homolog (Drosophila) 
 
National Institutes of Health

Related topics

Related topics

1 relation
CBX5 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
CBX8 Exhibits Oncogenic Activity via AKT/β-Catenin Activation in Hepatocellular Carcinoma.
Deregulation of polycomb proteins influences the development and progression of hepatocellular carcinoma. Here we show that… Expand
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Highly Cited
2016
Highly Cited
2016
EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis.
The EZH2 histone methyltransferase mediates the humoral immune response and drives lymphomagenesis through formation of bivalent… Expand
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2016
2016
Cbx8 Acts Non-canonically with Wdr5 to Promote Mammary Tumorigenesis.
Chromatin-mediated processes influence the development and progression of breast cancer. Using murine mammary carcinoma-derived… Expand
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Highly Cited
2015
Highly Cited
2015
Genomic Analyses Reveal Mutational Signatures and Frequently Altered Genes in Esophageal Squamous Cell Carcinoma
Esophageal squamous cell carcinoma (ESCC) is one of the most common cancers worldwide and the fourth most lethal cancer in China… Expand
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2014
2014
A Cbx8-Containing Polycomb Complex Facilitates the Transition to Gene Activation during ES Cell Differentiation
Polycomb proteins play an essential role in maintaining the repression of developmental genes in self-renewing embryonic stem… Expand
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Highly Cited
2013
Highly Cited
2013
Polycomb Cbx family members mediate the balance between haematopoietic stem cell self-renewal and differentiation
The balance between self-renewal and differentiation of adult stem cells is essential for tissue homeostasis. Here we show that… Expand
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Highly Cited
2007
Highly Cited
2007
Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A‐ARF locus
The Polycomb group (PcG) proteins are essential for embryogenesis, and their expression is often found deregulated in human… Expand
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Highly Cited
2006
Highly Cited
2006
Mouse Polycomb Proteins Bind Differentially to Methylated Histone H3 and RNA and Are Enriched in Facultative Heterochromatin
ABSTRACT The chromodomain (CD) of the Drosophila Polycomb protein exhibits preferential binding affinity for histone H3 when… Expand
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Highly Cited
2001
Highly Cited
2001
The ENL moiety of the childhood leukemia-associated MLL–ENL oncoprotein recruits human Polycomb 3
The translocation t(11;19) is frequently found in acute leukemia in infants. This event truncates the proto-oncogene MLL and… Expand
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Highly Cited
2000
Highly Cited
2000
HPC3 Is a New Human Polycomb Orthologue That Interacts and Associates with RING1 and Bmi1 and Has Transcriptional Repression Properties*
Polycomb group (PcG) proteins were first described in Drosophila as factors responsible for maintaining the transcriptionally… Expand
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