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CBP/beta-catenin Antagonist PRI-724

Known as: PRI-724 
A potent, specific inhibitor of the canonical Wnt signaling pathway in cancer stem cells with potential antineoplastic activity. Wnt signaling… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Leukemic Transformation of Post-Essential Thrombocythemia Myelofibrosis: A Unique Case Presenting with Double MPL and CALR Mutations
Background. Activating mutations in the thrombopoietin receptor (MPL), its proximal signaling partner Janus Kinase 2 (JAK2) or… 
2017
2017
Selective inhibitor of Wnt/β-catenin/CBP signaling ameliorates hepatitis C virus-induced liver fibrosis in mouse model
Chronic hepatitis C virus (HCV) infection is one of the major causes of serious liver diseases, including liver cirrhosis. There… 
2016
2016
Abstract A64: β-catenin as a TIC therapeutic target in epithelial ovarian cancer.
Epithelial ovarian cancer (EOC) is the most lethal gynecologic malignancy and is the fifth leading cause of cancer deaths in… 
2014
2014
377 Plucked hair as a platform for monitoring pharmacodynamic and mechanistic consequences of clinical exposure to the Wnt/beta-catenin inhibitor PRI-724
2014
2014
PRI-724 Significantly Reduces Retinal Fibrosis in Models of CNV and PVR
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