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CBFB gene

Known as: PEBP2B, Core-Binding Factor, Beta Subunit Gene, CBFB 
This gene is involved in hematopoiesis and osteogenesis.
National Institutes of Health

Related topics

Related topics

9 relations
Acute Myelomonocytic Leukemia with Abnormal EosinophilsCBFB protein, humanCBFB wt AlleleCBFB-MYH11 Fusion Protein Expression

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Clonal Evolution of Relapsed CBFB/MYH11 Rearranged Acute Myeloid Leukemia (AML)
The leukemia-associated fusion gene CBFB/MYH11 results from a pericentric inversion of chromosome 16, inv(16)(p13.1q22), or… 
2015
2015
Vif determines the requirement for CBF-β in APOBEC3 degradation.
APOBEC3 (apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3) proteins are cellular DNA deaminases that restrict a… 
2013
2013
RUNX1-RUNX1T1, and CBFB-MYH11 acute myeloid leukemias Strikingly different molecular relapse kinetics in NPM1c, PML-RARA,
2012
2012
Sole Trisomy 22 Not Associated with inv(16) in Myelodysplastic Syndrome
Trisomy 22 is closely associated with inv(16) or t(16;16) and could be a marker of cryptic rearrangement of CBFB/MYH11 in acute… 
2011
2011
CBFB and MYH11 in inv(16)(p13q22) of acute myeloid leukemia displaying close spatial proximity in interphase nuclei of human hematopoietic stem cells
To gain a better understanding of the mechanism of chromosomal translocations in cancer, we investigated the spatial proximity… 
2006
2006
Diagnosis and monitoring of CBFB-MYH11-positive acute myeloid leukemia by qualitative and quantitative RT-PCR.
During the last decade, many mutations present in myeloid leukemias have been molecularly characterized. Several of these… 
2003
2003
Rapid identification of CBFB-MYH11-positive acute myeloid leukemia (AML) cases by one single MYH11 real-time RT-PCR.
The inv(16)(p13q22) rearrangement is present in approximately 10% of cases with de novo acute myeloid leukemia (AML) and results… 
2000
2000
Deletion of 3'-CBFB gene in association with an inversion (16)(p13q22) and a loss of the Y chromosome in a 2-year-Old child with acute myelogenous leukemia-M4.
1998
1998
Identification of a novel CBFB-MYH11 fusion transcript in a patient with AML and inversion of chromosome 16
Identification of a novel CBFB-MYH11 fusion transcript in a patient with AML and inversion of chromosome 16 
1996
1996
The gene product of CBFB-MYH11.
The inversion(16)(p13;q22) gives rise to chimeric transcripts CBFB-MYH11. To date however, no reports have described the full… 
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