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CBFB gene

Known as: PEBP2B, Core-Binding Factor, Beta Subunit Gene, CBFB 
This gene is involved in hematopoiesis and osteogenesis.
National Institutes of Health

Related topics

Related topics

9 relations
Acute Myelomonocytic Leukemia with Abnormal EosinophilsCBFB protein, humanCBFB wt AlleleCBFB-MYH11 Fusion Protein Expression

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Monitoring of fusion gene transcripts to predict relapse in pediatric acute myeloid leukemia
In acute myeloid leukemia (AML), accurate detection of minimal residual disease (MRD) enables better risk‐stratified therapy… 
Review
2017
Review
2017
RUNX1 and CBFβ Mutations and Activities of Their Wild-Type Alleles in AML.
Mutations in RUNX1 and CBFB have long been recognized as important in hematological malignancies. Point mutations and deletions… 
2015
2015
Vif determines the requirement for CBF-β in APOBEC3 degradation.
APOBEC3 (apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3) proteins are cellular DNA deaminases that restrict a… 
2013
2013
RUNX1-RUNX1T1, and CBFB-MYH11 acute myeloid leukemias Strikingly different molecular relapse kinetics in NPM1c, PML-RARA,
2007
2007
CBFB-MYH11 hinders early T-cell development and induces massive cell death in the thymus.
Recent studies suggest that the chromosome 16 inversion, associated with acute myeloid leukemia M4Eo, takes place in… 
2006
2006
Diagnosis and monitoring of CBFB-MYH11-positive acute myeloid leukemia by qualitative and quantitative RT-PCR.
During the last decade, many mutations present in myeloid leukemias have been molecularly characterized. Several of these… 
2003
2003
Rapid identification of CBFB-MYH11-positive acute myeloid leukemia (AML) cases by one single MYH11 real-time RT-PCR.
The inv(16)(p13q22) rearrangement is present in approximately 10% of cases with de novo acute myeloid leukemia (AML) and results… 
1999
1999
Genomic acute myeloid leukemia-associated inv(16)(p13q22) breakpoints are tightly clustered
The inv(16) and related t(16;16) are found in 10% of all cases with de novo acute myeloid leukemia. In these rearrangements the… 
1998
1998
Identification of a novel CBFB-MYH11 fusion transcript in a patient with AML and inversion of chromosome 16
Identification of a novel CBFB-MYH11 fusion transcript in a patient with AML and inversion of chromosome 16 
1996
1996
The gene product of CBFB-MYH11.
The inversion(16)(p13;q22) gives rise to chimeric transcripts CBFB-MYH11. To date however, no reports have described the full… 
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