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CAY 10580

Known as: CAY-10580, CAY10580 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

DinoprostonePyrrolidinones
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
EP4 emerges as a novel regulator of bile acid synthesis and its activation protects against hypercholesterolemia.
2016
2016
Role of the prostaglandin E2 receptor agonists in TGF-β1-induced mesangial cell damage
PGE2 exerts its biological effect through binding to various EP receptors that result inactivation of various signal transduction… 
2015
2015
Activation of prostaglandin E2-EP4 signaling reduces chemokine production in adipose tissue[S]
Inflammation of adipose tissue induces metabolic derangements associated with obesity. Thus, determining ways to control or… 
2015
2015
Therapeutic intervention of proanthocyanidins on the migration capacity of melanoma cells is mediated through PGE2 receptors and β-catenin signaling molecules.
Melanoma is a highly aggressive form of skin cancer and a leading cause of death from skin diseases mainly due to its propensity… 
Highly Cited
2014
Highly Cited
2014
Downregulation of COX-2 and CYP 4A signaling by isoliquiritigenin inhibits human breast cancer metastasis through preventing anoikis resistance, migration and invasion.
2013
2013
Activation of prostaglandin E receptor 4 triggers secretion of gut hormone peptides GLP-1, GLP-2, and PYY.
Prostaglandins E1 and E2 are synthesized in the intestine and mediate a range of gastrointestinal functions via activation of the… 
Highly Cited
2011
Highly Cited
2011
Vasopressin-independent targeting of aquaporin-2 by selective E-prostanoid receptor agonists alleviates nephrogenic diabetes insipidus
In the kidney, the actions of vasopressin on its type-2 receptor (V2R) induce increased water reabsorption alongside… 
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