Skip to search formSkip to main contentSkip to account menu

CASC3 gene

Known as: CASC3, BTZ, MLN51 
This gene plays a role in nucleocytoplasmic shuttling of mRNA.
National Institutes of Health

Related topics

Related topics

9 relations
Breast CarcinomaCASC2 geneHomo sapiensIntracellular Transport

Narrower (1)

CASC3 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Ribosomal proteins produced in excess are degraded by the ubiquitin–proteasome system
Overexpression of ribosomal proteins in yeast is prevented by ubiquitination of unassembled ribosomal proteins in the nucleus and… 
Highly Cited
2016
Highly Cited
2016
Cross-class metallo-β-lactamase inhibition by bisthiazolidines reveals multiple binding modes
Significance Bacterial diseases remain a huge burden on healthcare worldwide, with the emergence and re-emergence of strains… 
Highly Cited
2015
Highly Cited
2015
BRAF-Activated Long Noncoding RNA Modulates Papillary Thyroid Carcinoma Cell Proliferation through Regulating Thyroid Stimulating Hormone Receptor
Purpose The importance of long noncoding RNAs (lncRNAs) in tumorigenesis has recently been demonstrated. However, the role of… 
Highly Cited
2014
Highly Cited
2014
Proteasome inhibitors in acute leukemia
Proteasome inhibition is a novel treatment for several hematological malignancies. However, resistance to the proteasome… 
Highly Cited
2012
Highly Cited
2012
Inactivating PSMB5 Mutations and P-Glycoprotein (Multidrug Resistance-Associated Protein/ATP-Binding Cassette B1) Mediate Resistance to Proteasome Inhibitors: Ex Vivo Efficacy of (Immuno)Proteasome…
Bortezomib (BTZ), a registered proteasome inhibitor (PI) for multiple myeloma, has also been proposed as a potential… 
Highly Cited
2010
Highly Cited
2010
Biological and structural characterization of the Mycobacterium smegmatis nitroreductase NfnB, and its role in benzothiazinone resistance
Tuberculosis is still a leading cause of death in developing countries, for which there is an urgent need for new pharmacological… 
Highly Cited
2009
Highly Cited
2009
The Hierarchy of Exon-Junction Complex Assembly by the Spliceosome Explains Key Features of Mammalian Nonsense-Mediated mRNA Decay
Protein complexes deposited on messenger RNAs during their maturation are able to recruit components of a cellular RNA… 
Highly Cited
2006
Highly Cited
2006
Functions of hUpf3a and hUpf3b in nonsense-mediated mRNA decay and translation.
The exon-junction complex (EJC) components hUpf3a and hUpf3b serve a dual function: They promote nonsense-mediated mRNA decay… 
Highly Cited
2006
Highly Cited
2006
Report on two novel nucleotide exchanges in the JAK2 pseudokinase domain: D620E and E627E
Report on two novel nucleotide exchanges in the JAK2 pseudokinase domain: D620E and E627E 
Highly Cited
2004
Highly Cited
2004
Association of the Breast Cancer Protein MLN51 with the Exon Junction Complex via Its Speckle Localizer and RNA Binding Module*
MLN51 is a nucleocytoplasmic shuttling protein that is overexpressed in breast cancer. The function of MLN51 in mammals remains… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)