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CAD106

 
National Institutes of Health

Papers overview

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Review
2019
Review
2019
Introduction Alzheimer's disease (AD) pathology, including the accumulation of amyloid beta (Aβ) species and tau pathology… Expand
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Review
2017
Review
2017
Amyloid beta peptide (Aβ) is produced through the proteolytic processing of a transmembrane protein, amyloid precursor protein… Expand
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2017
2017
INTRODUCTION This randomized, double-blind, placebo-controlled, 90-week study assessed safety, tolerability, and immunogenicity… Expand
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2015
2015
IntroductionCAD106 is designed to stimulate amyloid-β (Aβ)-specific antibody responses while avoiding T-cell autoimmune responses… Expand
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Review
2014
Review
2014
Both active and passive anti-β-amyloid (Aβ) immunotherapies for the treatment of Alzheimer's disease (AD) have demonstrated… Expand
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Review
2014
Review
2014
Dementia is a public health priority and one of the major contributors to morbidity and global non-communicable disease burden… Expand
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Highly Cited
2012
Highly Cited
2012
BACKGROUND Immunotherapy targeting the amyloid β (Aβ) peptide is a potential strategy to slow the progression of Alzheimer's… Expand
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2012
2012
Alzheimer disease: Amyloid-β immunotherapy CAD106 passes first safety test in patients with Alzheimer disease 
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2012
2012
Alzheimer’s disease is the most common cause of dementia globally, affecting about 36 million people at present and with about… Expand
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Highly Cited
2011
Highly Cited
2011
Immunization against amyloid-β (Aβ) can reduce amyloid accumulation in vivo and is considered a potential therapeutic approach… Expand
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