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C9orf142 gene

Known as: XLS, C9ORF142, PAXX 
National Institutes of Health

Papers overview

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2018
2018
Normal development of mice lacking PAXX, the paralogue of XRCC4 and XLF
DNA repair consists of several cellular pathways which recognize and repair damaged DNA. The classical nonhomologous DNA end… 
2017
2017
PAXX and Xlf interplay revealed by impaired CNS development and immunodeficiency of double KO mice
The repair of DNA double-stranded breaks (DNAdsb) through non-homologous end joining (NHEJ) is a prerequisite for the proper… 
2017
2017
Deficiency of XLF and PAXX prevents DNA double-strand break repair by non-homologous end joining in lymphocytes
ABSTRACT Non-homologous end joining (NHEJ) is a major DNA double-strand break (DSB) repair pathway that functions in all phases… 
Highly Cited
2016
Highly Cited
2016
Synthetic lethality between PAXX and XLF in mammalian development
Balmus et al. report that Paxx/Xlf double-knockout mice display embryonic lethality associated with genomic instability, cell… 
Highly Cited
2015
Highly Cited
2015
PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair
A factor for repairing broken DNA Unprogrammed DNA double-strand breaks are extremely dangerous for genomic stability… 
Highly Cited
2015
Highly Cited
2015
XLS (c9orf142) is a new component of mammalian DNA double-stranded break repair
Repair of double-stranded DNA breaks (DSBs) in mammalian cells primarily occurs by the non-homologous end-joining (NHEJ) pathway… 
Highly Cited
2014
Highly Cited
2014
Mental Stress in Atopic Dermatitis – Neuronal Plasticity and the Cholinergic System Are Affected in Atopic Dermatitis and in Response to Acute Experimental Mental Stress in a Randomized Controlled…
Rationale In mouse models for atopic dermatitis (AD) hypothalamus pituitary adrenal axis (HPA) dysfunction and neuropeptide… 
2014
2014
BICEP2, the curvature perturbation and supersymmetry
The tensor fraction r ≃ 0.16 found by BICEP2 corresponds to a Hubble parameter H ≃ 1.0 × 1014 GeV during inflation. This has two… 
Highly Cited
2008
Highly Cited
2008
Control of DFIG based wind generation to improve inter-area oscillation damping
In this paper, control of inter-area oscillation in power systems with high wind power penetration is achieved via doubly fed… 
Review
2002
Review
2002
Diversity and evolution of the -amylase genes in animals
Many living organisms show a tendency to have multiple amylase genes. It is also true in animals. In Drosophilids, the number of… 
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