FAQ

C-Terminal Binding Protein 2

Known as: C-Terminal-Binding Protein 2, CtBP2, Ribeye 
C-terminal-binding protein 2 (445 aa, ~49 kDa) is encoded by the human CTBP2 gene. This protein plays a role in the downregulation of both… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1987-2017
05101519872017

Related topics

Related topics

12 relations
CTBP2 geneCell NucleusGenes, RegulatorHeart
(More)

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
C-Terminal Binding Protein 2
Cell Nucleus
Pancreas
Skeletal muscle structure
Heart
Homo sapiens

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
C-terminal binding protein-2 regulates response of epithelial ovarian cancer cells to histone deacetylase inhibitors
Ovarian cancer survival rates have stagnated in the last 20 years despite the development of novel chemotherapeutic agents… (More)
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2008
2008
p19Arf inhibits the invasion of hepatocellular carcinoma cells by binding to C-terminal binding protein.
The INK4A/ARF tumor suppressor locus is frequently inactivated in hepatocellular carcinoma (HCC), yet the consequences of this… (More)
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Highly Cited
2008
Highly Cited
2008
Multiple loci identified in a genome-wide association study of prostate cancer
We followed our initial genome-wide association study (GWAS) of 527,869 SNPs on 1,172 individuals with prostate cancer and 1,157… (More)
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2007
2007
Identification of genes directly regulated by the oncogene ZNF217 using chromatin immunoprecipitation (ChIP)-chip assays.
It has been proposed that ZNF217, which is amplified at 20q13 in various tumors, plays a key role during neoplastic… (More)
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2006
2006
Targeting of C-terminal binding protein (CtBP) by ARF results in p53-independent apoptosis.
ARF encodes a potent tumor suppressor that antagonizes MDM2, a negative regulator of p53. ARF also suppresses the proliferation… (More)
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Highly Cited
2006
Highly Cited
2006
The nob2 mouse, a null mutation in Cacna1f: anatomical and functional abnormalities in the outer retina and their consequences on ganglion cell visual responses.
Glutamate release from photoreceptor terminals is controlled by voltage-dependent calcium channels (VDCCs). In humans, mutations… (More)
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2003
2003
The LIM protein FHL3 binds basic Krüppel-like factor/Krüppel-like factor 3 and its co-repressor C-terminal-binding protein 2.
The ability of DNA-binding transcription factors to recruit specific cofactors is central to the mechanism by which they regulate… (More)
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Highly Cited
2002
Highly Cited
2002
Overlapping and unique roles for C-terminal binding protein 1 (CtBP1) and CtBP2 during mouse development.
The C-terminal binding protein (CtBP) family of proteins has been linked to multiple biological processes through their… (More)
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Highly Cited
2000
Highly Cited
2000
RIBEYE, a Component of Synaptic Ribbons A Protein's Journey through Evolution Provides Insight into Synaptic Ribbon Function
Photoreceptor cells utilize ribbon synapses to transmit sensory signals at high resolution. Ribbon synapses release… (More)
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1998
1998
A novel C-terminal binding protein (CTBP2) is closely related to CTBP1, an adenovirus E1A-binding protein, and maps to human chromosome 21q21.3.
A region of the C-terminus of adenovirus type 2/5 E1A protein has been associated with negative modulation of tumorigenicity, as… (More)
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