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Bromisovalum
Known as:
2-Bromo-3-methylbutyrylurea
, Bromoisovalerylurea
, Bromisovalum [Chemical/Ingredient]
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A sedative and mild hypnotic with potentially toxic effects.
National Institutes of Health
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Related topics
Related topics
14 relations
Bromide poisoning
In Blood
agonists
analogs & derivatives
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Narrower (5)
Bromvaleton
Bromyl
Dolestan
Sedes A
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Broader (1)
Hypnotics and Sedatives
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
The hypnotic bromovalerylurea ameliorates 6-hydroxydopamine-induced dopaminergic neuron loss while suppressing expression of interferon regulatory factors by microglia
Hiromi Higaki
,
Mohammed E. Choudhury
,
+10 authors
Junya Tanaka
Neurochemistry International
2016
Corpus ID: 42040905
1995
1995
Effect of ifosfamide treatment on glutathione and glutathione conjugation activity in patients with advanced cancers.
T. Mulders
,
Keizer
,
J. Ouwerkerk
,
E. van der Velde
,
D. Breimer
,
G. Mulder
Clinical Cancer Research
1995
Corpus ID: 18555986
Several studies have suggested that the glutathione/glutathione S-transferase (GSH/GST) system is involved in resistance of…
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1992
1992
Rapid isolation with Sep-Pak C18 cartridges and wide-bore capillary gas chromatography of bromisovalum.
T. Kumazawa
,
H. Seno
,
O. Suzuki
Journal of Analytical Toxicology
1992
Corpus ID: 24097113
A simple and rapid method for isolation of bromisovalum with Sep-Pak C18 cartridges from human whole blood, plasma, and urine…
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1991
1991
Role of microtubuli in secretion of very‐low‐density lipoprotein in isolated rat hepatocytes: Early effects of thiol reagents
J. Nagelkerke
,
B. van de Water
,
+4 authors
G. Mulder
Hepatology
1991
Corpus ID: 43904319
The secretion of very‐low‐density lipoprotein from hepatocytes proceeds through the microtubules. In this study, the role of…
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1990
1990
Identification and differentiation of barbiturates, other sedative-hypnotics and their metabolites in urine integrated in a general screening procedure using computerized gas chromatography-mass…
H. Maurer
Journal of Chromatography A
1990
Corpus ID: 41673660
1989
1989
Stereoselectivity in the urinary excretion of the mercapturates of (R-) and (S-) alpha-bromoisovalerylurea in man.
J. te Koppele
,
C. Schipper
,
D. Breimer
,
G. Mulder
British Journal of Clinical Pharmacology
1989
Corpus ID: 44288013
1. alpha-Bromoisovalerylurea (BIU) is a racemic drug that is metabolized by glutathione conjugation. The urinary excretion of the…
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1988
1988
Inhibition of lipid peroxidation by disulfiram and diethyldithiocarbamate does not prevent hepatotoxin-induced cell death in isolated rat hepatocytes. A study with allyl alcohol, tert-butyl…
P. Dogterom
,
J. Nagelkerke
,
J. van Steveninck
,
G. Mulder
Chemico-Biological Interactions
1988
Corpus ID: 38607662
1988
1988
Stereoselectivity of rat liver glutathione transferase isoenzymes for alpha-bromoisovaleric acid and alpha-bromoisovalerylurea enantiomers.
J. te Koppele
,
B. Coles
,
B. Ketterer
,
G. Mulder
Biochemical Journal
1988
Corpus ID: 11949380
The stereoselectivity of purified rat GSH transferases towards alpha-bromoisovaleric acid (BI) and its amide derivative alpha…
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1988
1988
Liquid chromatographic determination of diastereomeric glutathione conjugates and further derivatives of alpha-bromoisovalerylurea in rat bile and urine by electrochemically generated bromine.
J. te Koppele
,
E. J. van der Mark
,
G. Mulder
Journal of Chromatography A
1988
Corpus ID: 22525857
1967
1967
Über den Nachweis und die quantitative Bestimmung bromierter Harnstoffderivate in der Toxikologie
W. Kisser
Fühner-Weilands Sammlung von Vergiftungsfällen…
1967
Corpus ID: 22611257
ZusammenfassungBromierte Harnstoffderivate (Carbromal und Bromisoval) und ihre Abbauprodukte werden im toxikologischen…
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