Break-Induced Replication

Known as: BIR, Break Induced Replication 
A type of DNA repair that uses homologous recombination to resolve chromosomal double strand breaks. This process involves the invasion of a… (More)
National Institutes of Health

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Highly Cited
2014
Highly Cited
2014
In budding yeast, one-ended DNA double-strand breaks (DSBs) and damaged replication forks are repaired by break-induced… (More)
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Highly Cited
2013
Highly Cited
2013
The repair of chromosomal double strand breaks (DSBs) is crucial for the maintenance of genomic integrity. However, the repair of… (More)
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Highly Cited
2011
Highly Cited
2011
DNA must be synthesized for purposes of genome duplication and DNA repair. While the former is a highly accurate process, short… (More)
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Highly Cited
2010
Highly Cited
2010
Break-induced replication (BIR) is an efficient homologous recombination (HR) pathway employed to repair a DNA double-strand… (More)
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Review
2008
Review
2008
Homologous recombination (HR) is considered to be an error-free mechanism for the repair of DNA double-strand breaks (DSBs… (More)
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Highly Cited
2007
Highly Cited
2007
DNA double-strand breaks (DSBs) are potentially lethal lesions that arise spontaneously during normal cellular metabolism, as a… (More)
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Review
2006
Review
2006
When a telomere becomes unprotected or if only one end of a chromosomal double-strand break succeeds in recombining with a… (More)
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Highly Cited
2005
Highly Cited
2005
Diploid Saccharomyces cells experiencing a double-strand break (DSB) on one homologous chromosome repair the break by RAD51… (More)
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Highly Cited
2004
Highly Cited
2004
A chromosome fragmentation assay was used to measure the efficiency and genetic control of break-induced replication (BIR) in… (More)
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Highly Cited
2002
Highly Cited
2002
Repair of double-strand breaks by gene conversions between homologous sequences located on different Saccharomyces cerevisiae… (More)
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