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Bone Marrow Purging

Known as: Purging, Bone Marrow, myeloablation 
Techniques for the removal of subpopulations of cells (usually residual tumor cells) from the bone marrow ex vivo before it is infused. The purging… 
National Institutes of Health

Related topics

Related topics

7 relations
Autograft MaterialHemopoietic stem cell transplantImmunomagnetic SeparationTransplantation, Autologous

Broader (1)

Bone Marrow Transplantation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2012
Review
2012
Effects of Myeloablation, Peripheral Chimerism, and Whole-Body Irradiation on the Entry of Bone Marrow-Derived Cells into the Brain
Understanding how bone marrow-derived cells (BMDCs) enter the central nervous system (CNS) is critical for the development of… 
2009
2009
Prostaglandin E 2 enhances hematopoietic stem cell homing , survival , and proliferation
Adult hematopoietic stem cells (HSCs) are routinely used to reconstitute hematopoiesis after myeloablation; however… 
Highly Cited
2000
Highly Cited
2000
Allogeneic hematopoietic chimerism in mice treated with sublethal myeloablation and anti-CD154 antibody: absence of graft-versus-host disease, induction of skin allograft tolerance, and prevention of…
We describe a tolerance-based stem cell transplantation protocol that combines sublethal radiation with transient blockade of the… 
Highly Cited
1997
Highly Cited
1997
Reverse transcriptase-polymerase chain reaction (RT-PCR)-controlled immunomagnetic purging of breast cancer cells using the magnetic cell separation (MACS) system: a sensitive method for monitoring…
A modified reverse transcriptase-polymerase chain reaction (RT-PCR) technique was established with the aim of monitoring the… 
Highly Cited
1996
Highly Cited
1996
Mechanism for cotolerance in nonlethally conditioned mixed chimeras: negative selection of the Vbeta T-cell receptor repertoire by both host and donor bone marrow-derived cells.
Bone marrow (BM) chimeras prepared by complete recipient ablation (A-->B) exhibit donor-specific tolerance, yet survival is often… 
Highly Cited
1995
Highly Cited
1995
Long-term in vivo expression of the human glucocerebrosidase gene in nonhuman primates after CD34+ hematopoietic cell transduction with cell-free retroviral vector preparations.
Successful gene transfer into stem cells would provide a potentially useful therapeutic modality for treatment of inherited and… 
Review
1994
Review
1994
The use of photodynamic therapy in bone marrow purging.
High-dose chemotherapy and autologous bone marrow transplantation are an effective combination for treating a number of malignant… 
1991
1991
High-dose therapy and autologous peripheral stem cell transplantation for patients with bone marrow metastases and relapsed lymphoma: an alternative to bone marrow purging.
Throughout a 4-year period, we reinfused autologous peripheral stem cells rather than purged autologous bone marrow following… 
1989
1989
Establishment of a reliable experimental procedure for bone marrow purging with mafosfamide (ASTA Z 7557).
Bone marrow purging with cyclophosphamide derivatives (Mafosfamide) requires the establishment of a defined experimental… 
Highly Cited
1986
Highly Cited
1986
Leukemia diagnosis and testing of complement-fixing antibodies for bone marrow purging in acute lymphoid leukemia.
In this paper a microplate method is described for diagnosing acute leukemia and for investigating the reactivity of monoclonal… 
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