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Bcl-2 Homology Domain

Proteins that are related to bcl-2 are characterized by the presence of one or more highly conserved stretches of homology with bcl-2, designated BH1… Expand
National Institutes of Health

Papers overview

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Review
2012
Review
2012
Fas (also called CD95 or APO-1), a member of a subgroup of the tumour necrosis factor receptor superfamily that contain an… Expand
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2011
2011
Bcl-2 homology domain 3 (BH3)-only proteins are pro-apoptotic Bcl-2 family members that play important roles in upstream cell… Expand
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Highly Cited
2010
Highly Cited
2010
Disturbances in cellular ion gradients by excitotoxicity promote apoptosis through activation of the Bcl-2 family member Bim. 
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2010
2010
The functional significance of neuronal death for pathogenesis of epilepsy and the underlying molecular mechanisms thereof remain… Expand
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2010
2010
Prolonged seizures (status epilepticus) are associated with brain region-specific regulation of apoptosis-associated signaling… Expand
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2007
2007
Cancer cell apoptosis can be induced by cisplatin, an efficient anticancer agent. However, its mechanism is not fully understood… Expand
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2006
2006
Bcl-2 homology domain (BH) 3-only proteins couple stress signals to evolutionarily conserved mitochondrial apoptotic pathways… Expand
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Highly Cited
2003
Highly Cited
2003
Endoplasmic reticulum (ER) stress has been implicated in the pathogenesis of ischemic and neurodegenerative disorders. Treatment… Expand
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Highly Cited
2000
Highly Cited
2000
Mcl-1 is a member of the Bcl-2 family that is regulated transcriptionally and post-transcriptionally, with expression of the full… Expand
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