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Bay X 1005
Known as:
Bay X1005
, BAYX-1005
, Bay-X1005
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National Institutes of Health
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2009
Review
2009
FLAP inhibitors for the treatment of inflammatory diseases.
A. Sampson
Current opinion in investigational drugs
2009
Corpus ID: 33308030
Leukotrienes are lipid inflammatory mediators that are implicated in asthma, COPD, arthritis, cardiovascular disease and cancer…
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2007
2007
Leukotriene inhibition in high-risk genotypes
P. Noseworthy
,
C. Newton-Cheh
2007
Corpus ID: 72990874
Methods: Investigators conducted a prospective, randomized, placebo-controlled, crossover trial of the leukotriene antagonist (DG…
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Highly Cited
2005
Highly Cited
2005
Effects of a 5-lipoxygenase-activating protein inhibitor on biomarkers associated with risk of myocardial infarction: a randomized trial.
H. Hakonarson
,
Sverrir Thorvaldsson
,
+25 authors
K. Stefánsson
JAMA
2005
Corpus ID: 44406463
Highly Cited
2005
Highly Cited
2005
The regulation of human MMP-13 by licofelone, an inhibitor of cyclo-oxygenases and 5-lipoxygenase, in human osteoarthritic chondrocytes is mediated by the inhibition of the p38 MAP kinase signalling…
C. Boileau
,
J. Pelletier
,
+4 authors
J. Martel-Pelletier
Annals of the Rheumatic Diseases
2005
Corpus ID: 39161580
Background: MMP-13 is one of the most important metalloproteases (MMP) involved in osteoarthritis. Licofelone, a novel dual…
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Highly Cited
2002
Highly Cited
2002
Study of the role of leukotriene B()4 in abnormal function of human subchondral osteoarthritis osteoblasts: effects of cyclooxygenase and/or 5-lipoxygenase inhibition.
Yosabeth Paredes
,
F. Massicotte
,
J. Pelletier
,
J. Martel-Pelletier
,
S. Laufer
,
D. Lajeunesse
Arthritis & Rheumatism
2002
Corpus ID: 22504517
OBJECTIVE To compare the effect of licofelone, NS-398 (an inhibitor of cyclooxygenase 2 [COX-2]), and BayX-1005 (an inhibitor of…
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Review
1997
Review
1997
Biosynthesis inhibitors for leukotrienes in bronchial asthma.
J. Negro
,
J. Miralles
,
J. Ortiz
,
E. Funes
,
A. García
Allergologia et Immunopathologia
1997
Corpus ID: 7685173
This article reviews the literature on the effects of leukotrienes in asthma. In particular, the ability of recently developed…
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