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BRCA3 gene

Known as: Breast Cancer 3 Gene, BRCA3, breast cancer 3 
This gene plays a role in tumor suppression.
National Institutes of Health

Related topics

Related topics

8 relations
BRCA3 ProteinBRCA3 wt AlleleBREAST CANCER 3Breast Carcinoma

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Cardiac Outcomes of Patients Receiving Adjuvant Weekly Paclitaxel and Trastuzumab for Node-Negative, ERBB2-Positive Breast Cancer.
IMPORTANCE Trastuzumab is a life-saving therapy but is associated with symptomatic and asymptomatic left ventricular ejection… 
Highly Cited
2015
Highly Cited
2015
Patient-derived xenografts reveal that intraductal carcinoma of the prostate is a prominent pathology in BRCA2 mutation carriers with prostate cancer and correlates with poor prognosis.
Review
2013
Review
2013
Risk of Pancreatic Cancer in Breast Cancer Families from the Breast Cancer Family Registry
Background: Increased risk of pancreatic cancer has been reported in breast cancer families carrying BRCA1and BRCA2 mutations… 
Highly Cited
2007
Highly Cited
2007
Immunohistochemical classification of non-BRCA1/2 tumors identifies different groups that demonstrate the heterogeneity of BRCAX families
Around 25% of hereditary breast and ovarian cancer families have mutations in the BRCA1 and BRCA2 genes. The search for other… 
Highly Cited
2005
Highly Cited
2005
A predictor based on the somatic genomic changes of the BRCA1/BRCA2 breast cancer tumors identifies the non-BRCA1/BRCA2 tumors with BRCA1 promoter hypermethylation.
The genetic changes underlying in the development and progression of familial breast cancer are poorly understood. To identify a… 
2005
2005
Comparison of genomic abnormalities between BRCAX and sporadic breast cancers studied by comparative genomic hybridization
Very little is known about the chromosomal regions harbouring genes involved in initiation and progression of BRCAX‐associated… 
Highly Cited
2003
Highly Cited
2003
Molecular classification of familial non-BRCA1/BRCA2 breast cancer
In the decade since their discovery, the two major breast cancer susceptibility genes BRCA1 and BRCA2, have been shown… 
Highly Cited
2002
Highly Cited
2002
Evaluation of linkage of breast cancer to the putative BRCA3 locus on chromosome 13q21 in 128 multiple case families from the Breast Cancer Linkage Consortium
The known susceptibility genes for breast cancer, including BRCA1 and BRCA2, only account for a minority of the familial… 
Highly Cited
2001
Highly Cited
2001
Evidence for further breast cancer susceptibility genes in addition to BRCA1 and BRCA2 in a population‐based study
We used data from a population based series of breast cancer patients to investigate the genetic models that can best explain… 
Review
2000
Review
2000
Founder populations and their uses for breast cancer genetics
Numerous founder mutations have been reported in BRCA1 and BRCA2. For genetic screening of a population with a founder mutation… 
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