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BRCA3 gene

Known as: Breast Cancer 3 Gene, BRCA3, breast cancer 3 
This gene plays a role in tumor suppression.
National Institutes of Health

Related topics

Related topics

8 relations
BRCA3 ProteinBRCA3 wt AlleleBREAST CANCER 3Breast Carcinoma

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
BRCA1/2-negative, high-risk breast cancers (BRCAX) for Asian women: genetic susceptibility loci and their potential impacts
“BRCAX” refers breast cancers occurring in women with a family history predictive of being a BRCA1/2 mutation carrier, but BRCA1… 
2015
2015
Detection of novel germline mutations for breast cancer in non‐BRCA1/2 families
The identification of the breast cancer susceptibility genes BRCA1 and BRCA2 enhanced clinicians' ability to select high‐risk… 
Review
2013
Review
2013
Risk of Pancreatic Cancer in Breast Cancer Families from the Breast Cancer Family Registry
Background: Increased risk of pancreatic cancer has been reported in breast cancer families carrying BRCA1and BRCA2 mutations… 
2012
2012
MUTYH gene variants and breast cancer in a Dutch case–control study
The MUTYH gene is involved in base excision repair. MUTYH mutations predispose to recessively inherited colorectal polyposis and… 
Highly Cited
2008
Highly Cited
2008
Promoter methylation-associated loss of ID4 expression is a marker of tumour recurrence in human breast cancer
BackgroundInhibitor of DNA binding/Inhibitor of differentiation 4 (ID4) is a critical factor for cell proliferation and… 
Highly Cited
2007
Highly Cited
2007
Immunohistochemical classification of non-BRCA1/2 tumors identifies different groups that demonstrate the heterogeneity of BRCAX families
Around 25% of hereditary breast and ovarian cancer families have mutations in the BRCA1 and BRCA2 genes. The search for other… 
2005
2005
Comparison of genomic abnormalities between BRCAX and sporadic breast cancers studied by comparative genomic hybridization
Very little is known about the chromosomal regions harbouring genes involved in initiation and progression of BRCAX‐associated… 
Highly Cited
2002
Highly Cited
2002
Evaluation of linkage of breast cancer to the putative BRCA3 locus on chromosome 13q21 in 128 multiple case families from the Breast Cancer Linkage Consortium
The known susceptibility genes for breast cancer, including BRCA1 and BRCA2, only account for a minority of the familial… 
Highly Cited
2001
Highly Cited
2001
Evidence for further breast cancer susceptibility genes in addition to BRCA1 and BRCA2 in a population‐based study
We used data from a population based series of breast cancer patients to investigate the genetic models that can best explain… 
Review
2000
Review
2000
Founder populations and their uses for breast cancer genetics
Numerous founder mutations have been reported in BRCA1 and BRCA2. For genetic screening of a population with a founder mutation… 
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