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BQ 485

Known as: BQ-485 
National Institutes of Health

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2 relations

Broader (2)

AzepinesOligopeptides

Papers overview

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Highly Cited
2005
Highly Cited
2005
Role of mitogen-activated protein kinase pathway in reactive oxygen species-mediated endothelin-1-induced beta-myosin heavy chain gene expression and cardiomyocyte hypertrophy.
Endothelin-1 (ET-1) has been found to increase cardiac beta-myosin heavy chain (beta-MyHC) gene expression and induce hypertrophy… 
2004
2004
Hemostasis in the absence of clotting factors.
BACKGROUND This study tests whether the hemostatic action of poly-N-acetyl glucosamine (p-GlcNAc) fiber material involves… 
2001
2001
Inotropic response of rabbit ventricular myocytes to endothelin-1: difference from isolated papillary muscles.
Endothelin-1 (ET-1) increased cell shortening and Ca2+ transients over the concentration of 3 x 10(-11) M to 10(-9) M with EC50… 
1999
1999
Functional characterization of endothelin receptors in hypertensive resistance vessels.
OBJECTIVE The physiological and pathophysiological functions of endothelin-1 in modulating the regional blood flow of normal and… 
1999
1999
Acetylcholine-induced endothelium-derived contracting factor in hypoxic pulmonary hypertensive rats.
We determined the role of an endothelium-derived contracting factor in the impaired relaxation response to ACh of conduit… 
1998
1998
In vitro effects of endothelin-1 on somatostatin and thyrotropin-releasing hormone release from the rat stomach.
1997
1997
Dual effects of endothelins on the muscarinic K+ current in guinea pig atrial cells.
Effects of endothelins (ETs) on the acetylcholine receptor-operated K+ current (I(KACh)) were examined in isolated guinea pig… 
Highly Cited
1996
Highly Cited
1996
Effect of selective blockade of endothelin ETB receptors on the liver dysfunction and injury caused by endotoxaemia in the rat
1 We investigated the effects of the selective endothelin (ET)A receptor antagonist BQ‐485 and the selective ETB receptor… 
1996
1996
Endothelin-1 partially inhibits ATP-sensitive K+ current in guinea pig ventricular cells.
To clarify the pathophysiological significance of endothelin (ET) in the ischemic myocardium, we examined the effect of… 
1995
1995
Endothelin-1 enhances nitric oxide-induced cytotoxicity in vascular smooth muscle.
Prolonged incubation with 1 nmol/L interleukin-1 induced high levels of nitric oxide release and cytotoxicity in vascular smooth… 
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