BPR0L075

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2004-2012
01220042012

Papers overview

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2013
2013
Paclitaxel plays a major role in the treatment of ovarian cancer; however, resistance to paclitaxel is frequently observed. Thus… (More)
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2012
2012
BPR0L075, 6-methoxy-3-(3',4',5'-trimethoxy-benzoyl)-1H-indole, is a tubulin-binding agent that inhibits tubulin polymerization by… (More)
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2012
2012
BPR0L075 [6-methoxy-3-(3',4',5'-trimethoxy-benzoyl)-1H-indole] is a novel anti-microtubule drug with anti-tumor and anti… (More)
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2011
2011
Utilizing scaffold-hopping drug-design strategy, we sought to identify a backup drug candidate for BPR0L075 (1), an indole-based… (More)
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2010
2010
BACKGROUND Antimitotic tubulin-binding BPR0L075 is structurally analogous to the vascular-disrupting combretastatin A-4… (More)
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2010
2010
BACKGROUND Anti-mitotic compounds (microtubule de-stabilizers) such as vincristine and vinblastine have been shown clinically… (More)
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2009
2009
Survivin is a dual function protein. It inhibits the apoptosis of cells by inhibiting caspases, and also promotes cell growth by… (More)
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2008
2008
6-Methoxy-3-(3',4',5'-trimethoxybenzoyl)-1H-indole (BPR0L075) (1) is a potent inhibitor of tubulin polymerization which exhibits… (More)
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2007
2007
A rapid and sensitive liquid chromatography-tandem mass spectrometric method (LC-MS/MS) had been developed and validated to… (More)
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2004
2004
BPR0L075 is a novel synthetic compound discovered through research to identify new microtubule inhibitors. BPR0L075 inhibits… (More)
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