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BMS-626529

National Institutes of Health

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2 relations

Broader (2)

PiperazinesTriazoles

Papers overview

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2017
2017
Improving diffraction limits by engineering crystallization chaperones – a case study of HIV1 envelope trimer and its application to drug design
The envelope (Env) protein of HIV-1 recognizes target cells and mediates cell fusion for viral entry and thus is an important… 
2017
2017
P-D3 Crystal structures of small-molecules HIV-1 entry ihibitor, BMS-378806 and BMS-626529, bound to BG505 SOSIP.664 HIV-1 Env trimer reveal an allosteric competitive etry inhibition mechanism
2015
2015
Structure and dynamics of the native HIV-1 Env trimer 2
11 HIV-1/AIDS remains one of the worst pandemics in human history. Despite tremendous efforts, 12 no effective vaccine has been… 
2014
2014
HIV-1 attachment inhibitor prodrug BMS-663068 in antiretroviral-experienced subjects: week 24 sub-group analysis
BMS‐663068 is a prodrug of BMS‐626529, an attachment inhibitor that binds directly to HIV‐1 gp120, preventing initial viral… 
2014
2014
Safety profile of HIV-1 attachment inhibitor prodrug BMS-663068 in antiretroviral-experienced subjects: week 24 analysis
BMS‐663068 is a prodrug of BMS‐626529, an attachment inhibitor that binds directly to HIV‐1 gp120, preventing initial viral… 
2013
2013
InhibitorsResistant to Other Entry CD4-Independent Viruses and HIV-1 Prodrug BMS-663068, against BMS-626529, the Active Component of the Activity of the HIV-1 Attachment Inhibitor
Highly Cited
2012
Highly Cited
2012
Pharmacodynamics, safety, and pharmacokinetics of BMS-663068, an oral HIV-1 attachment inhibitor in HIV-1-infected subjects.
BACKGROUND BMS-663068 is a prodrug of the small-molecule inhibitor BMS-626529, which inhibits human immunodeficiency virus type 1… 
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