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BMS 433771

Known as: BMS-433771, BMS433771 
 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Benzimidazoles

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Revealing the binding mode between respiratory syncytial virus fusion protein and benzimidazole-based inhibitors.
Human respiratory syncytial virus (HRSV) is a major respiratory pathogen in newborn infants and young children and can also be a… Expand
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2007
2007
Respiratory syncytial virus fusion inhibitors. Part 4: optimization for oral bioavailability.
A series of benzimidazole-based inhibitors of respiratory syncytial virus (RSV) fusion were optimized for antiviral potency… Expand
2007
2007
Respiratory syncytial virus fusion inhibitors. Part 6: an examination of the effect of structural variation of the benzimidazol-2-one heterocycle moiety.
The effect of structural variation of the benzimidazol-2-one ring of RSV fusion inhibitors related to BMS-433771 (1) was examined… Expand
2007
2007
Respiratory syncytial virus fusion inhibitors. Part 5: Optimization of benzimidazole substitution patterns towards derivatives with improved activity.
Extensive SAR studies and optimization of ADME properties of benzimidazol-2-one derivatives led to the identification of BMS… Expand
Review
2005
Review
2005
Filling the hole: evidence of a small molecule binding to the fusion core pocket in human respiratory syncytial virus
  • G. Gao
  • Expert opinion on investigational drugs
  • 2005
    • Corpus ID: 45601794
Searching for small molecules to inhibit envelope virus fusion has long been a frontier field for both academic research and the… Expand
Highly Cited
2004
Highly Cited
2004
Orally Active Fusion Inhibitor of Respiratory Syncytial Virus
ABSTRACT BMS-433771 was found to be a potent inhibitor of respiratory syncytial virus (RSV) replication in vitro. It exhibited… Expand
  • figure 1
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  • table 1
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  • table 2
Highly Cited
2004
Highly Cited
2004
Oral Efficacy of a Respiratory Syncytial Virus Inhibitor in Rodent Models of Infection
ABSTRACT BMS-433771 is a potent inhibitor of respiratory syncytial virus (RSV) replication in vitro. Mechanism of action studies… Expand
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