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BMS 433771
Known as:
BMS-433771
, BMS433771
National Institutes of Health
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Related topics
Related topics
1 relation
Broader (1)
Benzimidazoles
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Revealing the binding mode between respiratory syncytial virus fusion protein and benzimidazole-based inhibitors.
Dingjue Ji
,
W. Ye
,
Haifeng Chen
Molecular bioSystems
2015
Corpus ID: 19664935
Human respiratory syncytial virus (HRSV) is a major respiratory pathogen in newborn infants and young children and can also be a…
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2007
2007
Respiratory syncytial virus fusion inhibitors. Part 4: optimization for oral bioavailability.
Kuo-Long Yu
,
Ny Sin
,
+21 authors
N. Meanwell
Bioorganic & medicinal chemistry letters
2007
Corpus ID: 45432492
A series of benzimidazole-based inhibitors of respiratory syncytial virus (RSV) fusion were optimized for antiviral potency…
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2007
2007
Respiratory syncytial virus fusion inhibitors. Part 6: an examination of the effect of structural variation of the benzimidazol-2-one heterocycle moiety.
K. Combrink
,
H. Gulgeze
,
+17 authors
N. Meanwell
Bioorganic & medicinal chemistry letters
2007
Corpus ID: 40315156
The effect of structural variation of the benzimidazol-2-one ring of RSV fusion inhibitors related to BMS-433771 (1) was examined…
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2007
2007
Respiratory syncytial virus fusion inhibitors. Part 5: Optimization of benzimidazole substitution patterns towards derivatives with improved activity.
X. A. Wang
,
C. Cianci
,
+10 authors
N. Meanwell
Bioorganic & medicinal chemistry letters
2007
Corpus ID: 21308033
Extensive SAR studies and optimization of ADME properties of benzimidazol-2-one derivatives led to the identification of BMS…
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Review
2005
Review
2005
Filling the hole: evidence of a small molecule binding to the fusion core pocket in human respiratory syncytial virus
G. Gao
Expert opinion on investigational drugs
2005
Corpus ID: 45601794
Searching for small molecules to inhibit envelope virus fusion has long been a frontier field for both academic research and the…
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Highly Cited
2004
Highly Cited
2004
Orally Active Fusion Inhibitor of Respiratory Syncytial Virus
C. Cianci
,
Kuo-Long Yu
,
+21 authors
M. Krystal
Antimicrobial Agents and Chemotherapy
2004
Corpus ID: 27802177
ABSTRACT BMS-433771 was found to be a potent inhibitor of respiratory syncytial virus (RSV) replication in vitro. It exhibited…
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Highly Cited
2004
Highly Cited
2004
Oral Efficacy of a Respiratory Syncytial Virus Inhibitor in Rodent Models of Infection
C. Cianci
,
E. Genovesi
,
+13 authors
M. Krystal
Antimicrobial Agents and Chemotherapy
2004
Corpus ID: 23247584
ABSTRACT BMS-433771 is a potent inhibitor of respiratory syncytial virus (RSV) replication in vitro. Mechanism of action studies…
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