BMS 433771

Human respiratory syncytial virus (HRSV) is a major respiratory pathogen in newborn infants and young children and can also be a… Expand

A series of benzimidazole-based inhibitors of respiratory syncytial virus (RSV) fusion were optimized for antiviral potency… Expand

Extensive SAR studies and optimization of ADME properties of benzimidazol-2-one derivatives led to the identification of BMS… Expand

The effect of structural variation of the benzimidazol-2-one ring of RSV fusion inhibitors related to BMS-433771 (1) was examined… Expand

Searching for small molecules to inhibit envelope virus fusion has long been a frontier field for both academic research and the… Expand

BMS-433771 was found to be a potent inhibitor of respiratory syncytial virus (RSV) replication in vitro. It exhibited excellent… Expand

BMS-433771 is a potent inhibitor of respiratory syncytial virus (RSV) replication in vitro. Mechanism of action studies have… Expand