FAQ

BMP2 wt Allele

Known as: Bone Morphogenetic Protein 2A Gene, BMP2A, Bone Morphogenetic Protein 2 wt Allele 
Human BMP2 wild-type allele is located within 20p12 and is approximately 11 kb in length. This allele, which encodes bone morphogenetic protein 2, is… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2004-2018
01220042018

Related topics

Related topics

10 relations
20p12Cell Differentiation processCell Proliferation Regulatory ProcessDevelopmental process
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Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
BMP2 wt Allele
Cell Differentiation process
Receptor Signaling
Intercellular Communication Process
Homo sapiens
Developmental process

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
A novel duplication downstream of BMP2 in a Chinese family with Brachydactyly type A2 (BDA2).
BACKGROUND Brachydactyly type A2 (BDA2) is an autosomal dominant disease characterized by the deformation of the middle phalanx… (More)
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2015
2015
Two novel disease-causing variants in BMPR1B are associated with brachydactyly type A1
Brachydactyly type A1 is an autosomal dominant disorder primarily characterized by hypoplasia/aplasia of the middle phalanges of… (More)
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2014
2014
Identification of Duplication Downstream of BMP2 in a Chinese Family with Brachydactyly Type A2 (BDA2)
Brachydactyly type A2 (BDA2, MIM 112600) is characterized by the deviation and shortening of the middle phalange of the index… (More)
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2012
2012
Essential roles of zebrafish bmp2a, fgf10, and fgf24 in the specification of the ventral pancreas
In vertebrates, pancreas and liver arise from bipotential progenitors located in the embryonic gut endoderm. Bone morphogenic… (More)
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2011
2011
A 4.6 kb genomic duplication on 20p12.2-12.3 is associated with brachydactyly type A2 in a Chinese family.
BACKGROUND Brachydactyly type A2 (BDA2) is an autosomal dominant disorder. It was recently reported that a 5.9 kb duplication and… (More)
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2009
2009
Non-coding regulatory genetics of limb malformations.
The bone morphogenetic proteins (BMPs) are an important group of growth factors and secreted signaling molecules originally… (More)
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Highly Cited
2009
Highly Cited
2009
Duplications involving a conserved regulatory element downstream of BMP2 are associated with brachydactyly type A2.
Autosomal-dominant brachydactyly type A2 (BDA2), a limb malformation characterized by hypoplastic middle phalanges of the second… (More)
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Review
2006
Review
2006
A mutation in the receptor binding site of GDF5 causes Mohr-Wriedt brachydactyly type A2.
BACKGROUND Brachydactyly type A2 (OMIM 112600) is characterised by hypoplasia/aplasia of the second middle phalanx of the index… (More)
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2006
2006
A novel R486Q mutation in BMPR1B resulting in either a brachydactyly type C/symphalangism-like phenotype or brachydactyly type A2
Heterozygous missense mutations in the serine-threonine kinase receptor BMPR1B result typically in brachydactyly type A2 (BDA2… (More)
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2004
2004
Modulation of GDF5/BRI-b signalling through interaction with the tyrosine kinase receptor Ror2.
The brachydactylies are a group of inherited disorders of the hands characterized by shortened digits. Mutations in the tyrosine… (More)
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