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BML 210

Known as: BML-210, BML210 
National Institutes of Health

Papers overview

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2015
2015
The Histone Deacetylase Inhibitor BML-210 Influences Gene and Protein Expression in Human Promyelocytic Leukemia NB4 Cells via Epigenetic Reprogramming
Today, cancer is understood as an epigenetic as well as genetic disease. The main epigenetic hallmarks of the cancer cell are DNA… 
2014
2014
Numerical Modelling of Fuel Injection and Stratified Turbulent Combustion in a Direct-Injection Spark-Ignition Engine Using an Open Source Code
Stringent regulations on the emission of pollutants, especially carbon dioxide (CO2), necessitate the development of advanced… 
2012
2012
DNA methyltransferase inhibitor RG108 and histone deacetylase inhibitors cooperate to enhance NB4 cell differentiation and E‐cadherin re‐expression by chromatin remodelling
Epigenetic silencing of cancer‐related genes by abnormal methylation and the reversal of this process by DNA methylation… 
2012
2012
Antileukemic activity of combined epigenetic agents, DNMT inhibitors zebularine and RG108 with HDAC inhibitors, against promyelocytic leukemia HL-60 cells
DNMT inhibitors are promising new drugs for cancer therapies. In this study, we have observed the antileukemic action of two… 
2010
2010
Battle Management Language – Command and Control Graphical user Interface ( BMLC 2 GUI )
Battle Management Language (BML) and related technologies under development for the past few years have been shown to provide a… 
2008
2008
Characterization of proteins involved in differentiation and apoptosis of human leukemia and epithelial cancer cells
Today, cancer is understood as an epigenetic as well as a genetic disease. The main epigenetic hallmarks of the cancer cell are… 
2008
2008
Apoptotic effects of the novel histone deacetylase inhibi­ tor BML­210 on HeLa cells
Histone deacetylase inhibitors (HDACI) have been shown to inhibit cancer cell proliferation, induce cell cycle arrest, and… 
2006
2006
The novel histone deacetylase inhibitor BML-210 exerts growth inhibitory, proapoptotic and differentiation stimulating effects on the human leukemia cell lines.
2005
2005
Effects of retinoic acid and histone deacetylase inhibitor Bml-210 on protein expression in NB 4 cells
The acute promyelocytic leukemia cell line NB4 can differentiate to granulocytes in response to retinoic acid (RA) or to… 
2005
2005
Effects of retinoic acid and histone deacetylase inhibitor Bml-210 on protein expression in NB4 cells
Today, cancer is understood as an epigenetic as well as a genetic disease. The main epigenetic hallmarks of the cancer cell are… 
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