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BM-1197

National Institutes of Health

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Aniline CompoundsSulfonamides

Papers overview

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2015
2015
First MCL-1-selective BH3 mimetics as potential therapeutics for targeted treatment of cancer
First MCL-1-selective BH3 mimetics as potential therapeutics for targeted treatment of cancer 
2015
2015
BH3-mimetic small molecule inhibits the growth and recurrence of adenoid cystic carcinoma.
Highly Cited
2014
Highly Cited
2014
BM-1197: A Novel and Specific Bcl-2/Bcl-xL Inhibitor Inducing Complete and Long-Lasting Tumor Regression In Vivo
Bcl-2 and Bcl-xL are critical regulators of apoptosis that are overexpressed in a variety of human cancers and pharmacological… 
2014
2014
The small-molecule compound BM-1197 inhibits the antiapoptotic regulators Bcl-2/Bcl-xL and triggers apoptotic cell death in human colorectal cancer cells
Small molecule BH3 mimetics comprise a promising new chemotherapeutic strategy for treating relapsed or chemoresistant cancer. In… 
2012
2012
412 Antitumor Activity of BM-1197, a Dual Inhibitor of Bcl-2 and Bcl-xL, in Small Cell Lung Cancer Tumors
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