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BIO 7662

Known as: BIO-7662, BIO7662 
National Institutes of Health

Papers overview

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2005
2005
Design, Synthesis, and Analysis of a Polyethelene Glycol-Modified (PEGylated) Small Molecule Inhibitor of Integrin α4β1 with Improved Pharmaceutical Properties
Integrin α4β1 plays an important role in inflammatory processes by regulating the migration of leukocytes into inflamed tissues… 
2003
2003
A Small Molecule α4β1/α4β7 Antagonist Differentiates between the Low-Affinity States of α4β1 and α4β7: Characterization of Divalent Cation Dependence
An α4β1/α4β7 dual antagonist, 35S-compound 1, was used as a model ligand to study the effect of divalent cations on the… 
2003
2003
A small molecule alpha4beta1/alpha4beta7 antagonist differentiates between the low-affinity states of alpha4beta1 and alpha4beta7: characterization of divalent cation dependence.
An alpha4beta1/alpha4beta7 dual antagonist, 35S-compound 1, was used as a model ligand to study the effect of divalent cations on… 
2001
2001
Evidence that ligand and metal ion binding to integrin alpha 4beta 1 are regulated through a coupled equilibrium.
We have used the highly selective alpha(4)beta(1) inhibitor 2S-[(1-benzenesulfonyl-pyrrolidine-2S-carbonyl)-amino]-4-[4-methyl-2S… 
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