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BIO 5192

Known as: BIO-5192, BIO5192 
National Institutes of Health

Papers overview

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2009
2009
BIO 5192 , a small molecule inhibitor of VLA-4 , mobilizes hematopoietic stem and progenitor cells
Here we show that interruption of the VCAM-1/VLA-4 axis with a small molecule inhibitor of VLA-4, BIO5192, results in a 30-fold… 
2009
2009
HSC mobilization: new incites and insights.
In this issue of Blood, Ramirez and colleagues unveil a new small molecule antagonist of VCAM-1/VLA-4 signaling, BIO5192, that… 
2005
2005
Design, Synthesis, and Analysis of a Polyethelene Glycol-Modified (PEGylated) Small Molecule Inhibitor of Integrin α4β1 with Improved Pharmaceutical Properties
Integrin α4β1 plays an important role in inflammatory processes by regulating the migration of leukocytes into inflamed tissues… 
2005
2005
Design, synthesis, and analysis of a polyethelene glycol-modified (PEGylated) small molecule inhibitor of integrin {alpha}4{beta}1 with improved pharmaceutical properties.
Integrin alpha4beta1 plays an important role in inflammatory processes by regulating the migration of leukocytes into inflamed… 
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