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BIM 23056

Known as: BIM-23056 
 
National Institutes of Health

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1 relation

Broader (1)

Oligopeptides

Papers overview

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2004
2004
Somatostatin inhibits glutamate release from mouse cerebrocortical nerve endings through presynaptic sst2 receptors linked to the adenylyl cyclase–protein kinase A pathway
The effects of somatostatin (SRIF, somatotropin release inhibiting factor) on the release of glutamate have been investigated… Expand
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2001
2001
Somatostatin activates two types of inwardly rectifying K+ channels in MIN-6 cells.
Western blotting revealed the presence of five somatostatin receptor types, sst1, sst2, sst3, sst4 and sst5, in the mouse… Expand
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2000
2000
Somatostatin potentiates NMDA receptor function via activation of InsP(3) receptors and PKC leading to removal of the Mg(2+) block without depolarization.
N-methyl-D-aspartate (NMDA) receptors exist on noradrenergic axon terminals and mediate enhancement of noradrenaline (NA) release… Expand
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1999
1999
Activation of adenylate cyclase by human recombinant sst5 receptors expressed in CHO-K1 cells and involvement of Galphas proteins.
1. The coupling of the human somatostatin sst5 receptor recombinantly expressed in Chinese hamster ovary (CHO-K1) cells to… Expand
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1998
1998
Effect of 17beta-estradiol on somatostatin receptor expression and inhibitory effects on growth hormone and prolactin release in rat pituitary cell cultures.
In the present study, we tested whether 17beta-estradiol (E2)-induced PRL sensitivity to somatostatin-14 (SRIF) involves… Expand
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1997
1997
Somatostatin sst5 inhibition of receptor mediated regeneration of rat aortic vascular smooth muscle cells.
1. The aim of the present study was to determine the effect of somatostatin (SRIF) on mitogen-induced regeneration of rat aortic… Expand
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1996
1996
Potent antagonism by BIM-23056 at the human recombinant somatostatin sst5 receptor.
We have investigated the effects of somatostatin (SRIF) and the linear octapeptide BIM-23056 on changes in intracellular calcium… Expand
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1996
1996
A quantitative autoradiographical study on the distribution of somatostatin sst2 receptors in the rat central nervous system using [125I]-BIM-23027
The kinetic properties, steady state binding characteristics and autoradiographic distribution of the somatostatin (SRIF) sst2… Expand
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1996
1996
Somatostatin sst2 receptor-mediated inhibition of parietal cell function in rat isolated gastric mucosa.
1. The aim of this study was to determine the location and functional characteristics of the somatostatin (SRIF) receptor type(s… Expand
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1995
1995
Somatostatin-induced contraction of human isolated saphenous vein involves sst2 receptor-mediated activation of L-type calcium channels.
A range of somatostatin (SRIF) analogues have been used to characterize the SRIF receptor-mediating contraction of the human… Expand
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