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BI 69A11

Known as: BI-69A11 
National Institutes of Health

Papers overview

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2015
2015
Amplification of PI3K-Akt pathway promotes radioresistance in various cancers including colorectal carcinoma. Local recurrence in… 
2014
2014
Background:Akt and its downstream signalling pathways contribute to the aetiology and progression of colorectal carcinoma (CRC… 
2013
2013
To date, there are no effective therapies for tumors bearing NRAS mutations, which are present in 15–20% of human melanomas. Here… 
2013
2013
The protein Kinase B alpha (AKT) and nuclear factor kappa‐light‐chain‐enhancer of activated B cells (NF‐κB) pathways are central… 
2011
2011
In melanoma, the activation of pro‐survival signaling pathways, such as the AKT and NF‐κB pathways, is critical for tumor growth… 
2009
2009
The AKT/PKB pathway plays a central role in tumor development and progression and is often up‐regulated in different tumor types…