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BI 69A11

Known as: BI-69A11 
 
National Institutes of Health

Papers overview

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2019
2019
Epithelial to mesenchymal transition (EMT) is compulsory for metastatic dissemination and is stimulated by TGF-β. Although… Expand
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2015
2015
Amplification of PI3K-Akt pathway promotes radioresistance in various cancers including colorectal carcinoma. Local recurrence in… Expand
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2015
2015
BI-69A11, novel Akt inhibitor, is currently drawing much attention due to its intriguing effect in inducing apoptosis in melanoma… Expand
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2014
2014
Background:Akt and its downstream signalling pathways contribute to the aetiology and progression of colorectal carcinoma (CRC… Expand
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2013
2013
To date, there are no effective therapies for tumors bearing NRAS mutations, which are present in 15-20% of human melanomas. Here… Expand
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2013
2013
The protein Kinase B alpha (AKT) and nuclear factor kappa‐light‐chain‐enhancer of activated B cells (NF‐κB) pathways are central… Expand
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2011
2011
In melanoma, the activation of pro-survival signaling pathways, such as the AKT and NF-κB pathways, is critical for tumor growth… Expand
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2009
2009
The AKT/PKB pathway plays a central role in tumor development and progression and is often up-regulated in different tumor types… Expand
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