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BI 69A11

Known as: BI-69A11 
National Institutes of Health

Papers overview

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2016
2016
Cooperative effect of BI-69A11 and celecoxib enhances radiosensitization by modulating DNA damage repair in colon carcinoma
Amplification of PI3K-Akt pathway promotes radioresistance in various cancers including colorectal carcinoma. Local recurrence in… 
2015
2015
Blockade of autophagy enhances proapoptotic potential of BI-69A11, a novel Akt inhibitor, in colon carcinoma.
2011
2011
Effective inhibition of melanoma by BI‐69A11 is mediated by dual targeting of the AKT and NF‐κB pathways
In melanoma, the activation of pro‐survival signaling pathways, such as the AKT and NF‐κB pathways, is critical for tumor growth… 
2009
2009
BI‐69A11‐mediated inhibition of AKT leads to effective regression of xenograft melanoma
The AKT/PKB pathway plays a central role in tumor development and progression and is often up‐regulated in different tumor types… 
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