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BEST2 gene

Known as: VMD2-LIKE GENE 1, BEST2, VMD2L1 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Application of weighted gene co-expression network analysis to explore the potential diagnostic biomarkers for colorectal cancer
Colorectal cancer (CRC) is one of the most common malignant diseases in the world. Although mechanistic studies have been… 
Review
2015
Review
2015
Eccrine sweat gland development and sweat secretion
Eccrine sweat glands help to maintain homoeostasis, primarily by stabilizing body temperature. Derived from embryonic ectoderm… 
2015
2015
Sweating chloride bullets: understanding the role of calcium in eccrine sweat glands and possible implications for hyperhidrosis
Eccrine (atrichial) sweat glands are large, active cutaneous endorgans vital to human thermal and fluid homeostasis, but regional… 
Highly Cited
2012
Highly Cited
2012
Forkhead transcription factor FoxA1 regulates sweat secretion through Bestrophin 2 anion channel and Na-K-Cl cotransporter 1
Body temperature is maintained in a narrow range in mammals, primarily controlled by sweating. In humans, the dynamic… 
2010
2010
Bestrophin 2 is expressed in human non-pigmented ciliary epithelium but not retinal pigment epithelium
Purpose Mice in which bestrophin 2 (Best2) is disrupted exhibit changes in aqueous flow and drainage, resulting in a reduction in… 
2009
2009
Bestrophin 2: An anion channel associated with neurogenesis in chemosensory systems
The chemosensory neuroepithelia of the vertebrate olfactory system share a life‐long ability to regenerate. Novel neurons… 
Review
2009
Review
2009
Functional roles of bestrophins in ocular epithelia
2007
2007
Expression of three distinct families of calcium-activated chloride channel genes in the mouse dorsal root ganglion
ObjectiveA calcium-activated chloride current (ICl(Ca)) has been observed in medium-sized sensory neurons of the dorsal root… 
Highly Cited
2007
Highly Cited
2007
Small‐conductance Cl– channels contribute to volume regulation and phagocytosis in microglia
The shape and volume of microglia (brain immune cells) change when they activate during brain inflammation and become migratory… 
Highly Cited
2002
Highly Cited
2002
Three novel human VMD2-like genes are members of the evolutionary highly conserved RFP-TM family
The RFP-TM protein family was first described in Caenorhabditis elegans as hypothetical transmembrane proteins containing a… 
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